Aktivieren Sie Javascript in Ihrem Browser, um unsere Webseite optimal zu nutzen.

IKK alpha Antikörper (C-Term)

Name: IKK alpha Antikörper (C-Term)
SKU: ABIN116874
Availability: InStock

Der Kaninchen Polyklonal anti-IKK alpha Antikörper (ABIN116874) detektiert spezifisch IKK alpha in WB, IP und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Produktnummer ABIN116874

1.147,69 €

Zzgl. Versandkosten 20,00 € und MwSt

0.1 mL

Lieferung nach: Deutschland

Lieferung in 16 Werktagen

Kurzübersicht für IKK alpha Antikörper (C-Term) (ABIN116874)

Target

Alle IKK alpha (CHUK) Antikörper anzeigen

IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))

Reaktivität

Human, Maus, Ratte

Wirt

Kaninchen

Klonalität

Polyklonal

Konjugat

Dieser IKK alpha Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Discover our top product CHUK Primärantikörper

Bindungsspezifität
15

15

14

9

8

8

7

7

5

5

5

4

3

3

3

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
C-Term

Spezifität

Anti-IKKa may react non-specifically with other proteins. Control peptide will compete only with the specific reaction of antiserum with the IKKa subunit.

Aufreinigung

Prepared from monospecific antiserum by delipidation and defibrination.

Immunogen

IKKa peptide corresponding to the highly conserved C-terminus region of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH).
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (C-Term) antibody
CHUK Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (pSer176), (pSer177) antibody
CHUK Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (AA 646-745) antibody
CHUK Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 4B8 unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) antibody
KD Validated CHUK Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 23GB765 unconjugated Recombinant Antibody

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) antibody
KD Validated CHUK Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 23GB1065 unconjugated Recombinant Antibody

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (AA 646-745) antibody
CHUK Reaktivität: Human WB, ELISA, IF, PLA Wirt: Maus Monoclonal 1F8 unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (pThr23) antibody
CHUK Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) antibody
CHUK Reaktivität: Human WB, ELISA, ICC, FACS Wirt: Maus Monoclonal 3G12H9 unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (AA 411-745) antibody
CHUK Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (AA 411-745) antibody
CHUK Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Suitable for Immunoprecipitation, Immunoblotting and ELISA. Recommended Dilutions: This product was assayed by immunoblot and found to bereactive against IKKa at a dilution of 1: 1000 followed by reaction with Peroxidaseconjugated Affinity Purified anti-Rabbit IgG [H&L] (Goat). Anti-IKKa is suitable for thedetection by immunoblot of human, mouse and rat IKKa showing an 85 kDa band.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

80.0 mg/mL (by Refractometry)

Handhabung

Avoid repeated freezing and thawing.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store lyophilized product at 2-8 °C. After reconstitution, store at -20 °C.
Target

IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))

Andere Bezeichnung

IKKA

Hintergrund

NFk B comprises a family of cellular transcription factors that are involved in the inducible expression of a variety of cellular genes that regulate the inflammatory response and control of cell death. In the cytoplasm NFk B is negatively modulated by the inhibitory proteins Ik B. In turn Ik B is phosphorylated by a cellular kinase complex called IKK. IKK is a heterodimer composed of two kinases: IKK-a and IKK-b that phosphorylate Ik B leading to its degradation and the resulting translocation of NFk B to the nucleus. IKK kinase activity is modulated negatively by pharmaceutical agents such as aspirin and positively by various cellular components such as TNF-a , endotoxins and overexpression of cellular kinases like MEKK1. Aspirin appears to have its effect by inhibiting the binding of ATP to IKK.Synonyms: CHUK, Conserved helix-loop-helix ubiquitous kinase, I kappa-B kinase alpha, I-kappa-B kinase 1, IKK-A, IKK-alpha, IKK1, IkBKA, IkappaB kinase, Inhibitor of nuclear factor kappa-B kinase subunit alpha, NFKBIKA, Nuclear factor NF-kappa-B inhibitor kinase alpha, TCF16

Gen-ID

1147

NCBI Accession

NP_001269

UniProt

O15111

Pathways

PI3K-Akt Signalweg, NF-kappaB Signalweg, RTK Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteine