Galectin, Galactoside-Binding, Soluble, 3 (LGALS3) Antikörper

Antigen: Galectin, Galactoside-Binding, Soluble, 3 (LGALS3)

Synonyme: galectin-3, LGALS3, Galectin-3, MGC148757, leg3

Klonalität: Monoklonal (9C4)

Wirt: Maus

Reaktivität: Human

Applikation: Immunhistochemie (Paraffinschnitte) (IHC (p))

Produktnummer: ABIN99547

Produktbeschreibung

Weitere Bezeichnung: Galectin-3

Immunogen: BALB/C mice were immunized with prokaryotic recombinant fusion protein corresponding to the full-length galectin-3 molecule.

Format: Supernatant

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: 9C4

Spezifität: Galactin-3 is a member of the beta-galactosidase binding lectin family. Cell surface galectin-3 may be involved in homotypical cell adhesion and is down

Anwendungen

Applikationshinweise: Titer/Working Dilution: This antibody may be diluted to a titer of 1:50-1:75 in an ABC method. However, depending on the staining conditions employed, we suggest that final dilution should be determined by the user. Staining Protocol: We suggest an incubation period of 60 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Positive Control: Prostate. Cellular localization: Cytoplasmic

Konzentration: 100ug/ml approximately

Buffer: This antibody is supplied as tissue culture supernatant containing sodium azide as preservative.

Lagerung: Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.

Forschungsgebiet: Neurologie

Beschränkungen: Für Forschungszwecke. Als CE-zertifizierter Antikörper in der Europäischen Union für In Vitro Diagnostik (IVD) zugelassen.

Publikationen

Publikationen: Castronovo, Van Den Bruule, Jackers et al.: "Decreased expression of galectin-3 is associated with progression of human breast cancer." in: The Journal of pathology, Vol. 179, Issue 1, pp. 43-8, 1996 (PubMed).

Kasper, Hughes: "Immunocytochemical evidence for a modulation of galectin 3 (Mac-2), a carbohydrate binding protein, in pulmonary fibrosis." in: The Journal of pathology, Vol. 179, Issue 3, pp. 309-16, 1996 (PubMed).

Gasbarri, Martegani, Del Prete et al.: "Galectin-3 and CD44v6 isoforms in the preoperative evaluation of thyroid nodules." in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 17, Issue 11, pp. 3494-502, 2000 (PubMed).