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Ubiquitin B Antikörper

UBB Reaktivität: Human WB, ELISA, FACS Wirt: Maus Monoclonal 3C12 unconjugated
Produktnummer ABIN969573
  • Target Alle Ubiquitin B (UBB) Antikörper anzeigen
    Ubiquitin B (UBB)
    Reaktivität
    • 47
    • 25
    • 19
    • 13
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 42
    • 15
    Maus
    Klonalität
    • 36
    • 21
    Monoklonal
    Konjugat
    • 30
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Ubiquitin B Antikörper ist unkonjugiert
    Applikation
    • 36
    • 19
    • 19
    • 15
    • 10
    • 10
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human UBB expressed in E. coli.
    Klon
    3C12
    Isotyp
    IgG1
    Top Product
    Discover our top product UBB Primärantikörper
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Choudhary, Kumar, Gnad, Nielsen, Rehman, Walther, Olsen, Mann: "Lysine acetylation targets protein complexes and co-regulates major cellular functions." in: Science (New York, N.Y.), Vol. 325, Issue 5942, pp. 834-40, (2009) (PubMed).

    Komander: "The emerging complexity of protein ubiquitination." in: Biochemical Society transactions, Vol. 37, Issue Pt 5, pp. 937-53, (2009) (PubMed).

  • Target
    Ubiquitin B (UBB)
    Andere Bezeichnung
    UBB (UBB Produkte)
    Synonyme
    AL033289 antikoerper, Rps27a antikoerper, Uba52 antikoerper, Ubb2 antikoerper, Ubc antikoerper, UBC antikoerper, Ubiquitin antikoerper, UBB antikoerper, Ubi-p63E antikoerper, im:6892314 antikoerper, si:ch211-202a12.3 antikoerper, ubc antikoerper, zUBC antikoerper, zgc:172187 antikoerper, ubiquitin B antikoerper, ubiquitin C antikoerper, UBB antikoerper, Ubb antikoerper, UBC antikoerper, ubb antikoerper
    Hintergrund

    Description: This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome.

    Aliases: UBC, UBA52, RPS27A

    Molekulargewicht
    26 kDa
    Gen-ID
    7314
    HGNC
    7314
    Pathways
    Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, Toll-Like Receptors Cascades, Synthesis of DNA, Autophagie, EGFR Downregulation, Ubiquitin Proteasome Pathway
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