Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

MELK Antikörper (AA 637-651)

MELK Reaktivität: Human ELISA, IHC, ICC, FACS Wirt: Maus Monoclonal 2G2 unconjugated
Produktnummer ABIN969538
  • Target Alle MELK Antikörper anzeigen
    MELK (Maternal Embryonic Leucine Zipper Kinase (MELK))
    Bindungsspezifität
    • 15
    • 8
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 637-651
    Reaktivität
    • 62
    • 18
    • 14
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    Human
    Wirt
    • 62
    • 4
    • 1
    Maus
    Klonalität
    • 62
    • 5
    Monoklonal
    Konjugat
    • 36
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MELK Antikörper ist unkonjugiert
    Applikation
    • 40
    • 29
    • 13
    • 13
    • 7
    • 7
    • 7
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Sequenz
    VYKRLVEDIL SSCKV
    Immunogen
    Synthesized peptide of human MELK(AA: 637-651:C-VYKRLVEDILSSCKV).
    Klon
    2G2
    Isotyp
    IgG2a
  • Applikationshinweise
    ELISA: 1:10000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Nakano, Joshi, Visnyei, Hu, Watanabe, Lam, Wexler, Saigusa, Nakamura, Laks, Mischel, Viapiano, Kornblum: "Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway." in: Neuro-oncology, Vol. 13, Issue 6, pp. 622-34, (2011) (PubMed).

    Pickard, Green, Ellis, Caldas, Hedge, Mourtada-Maarabouni, Williams: "Dysregulated expression of Fau and MELK is associated with poor prognosis in breast cancer." in: Breast cancer research : BCR, Vol. 11, Issue 4, pp. R60, (2009) (PubMed).

  • Target
    MELK (Maternal Embryonic Leucine Zipper Kinase (MELK))
    Andere Bezeichnung
    MELK (MELK Produkte)
    Synonyme
    MELK antikoerper, xmelk antikoerper, Melk antikoerper, HPK38 antikoerper, AI327312 antikoerper, MPK38 antikoerper, mKIAA0175 antikoerper, fb71b01 antikoerper, fe01f04 antikoerper, wu:fb71b01 antikoerper, wu:fe01f04 antikoerper, maternal embryonic leucine zipper kinase antikoerper, maternal embryonic leucine zipper kinase L homeolog antikoerper, MELK antikoerper, melk antikoerper, cgd5_2270 antikoerper, Melk antikoerper, melk.L antikoerper
    Hintergrund

    Description: Maternal embryonic leucine-zipper kinase (MELK) is a key regulator of survival of stemlike GBM cells in vitro. MELK expression is increased in breast cancer tissue and this increase is also associated with poor patient survival, as predicted for a candidate oncogene.

    Aliases: HPK38

    Molekulargewicht
    74.6 kDa
    Gen-ID
    9833
    HGNC
    9833
Sie sind hier:
Kundenservice