GRIA2 Antikörper (Glutamate Receptor, Ionotropic, AMPA 2) (AA 652-807)

Details for Product anti-GRIA2 Antibody No. ABIN969524, Anbieter: Anmelden zum Anzeigen
Antigen
  • GLUR2
  • GluA2
  • GLURB
  • GluR-K2
  • HBGR2
  • GluR2
  • gluR-B
  • glur2
  • GluR-2
  • GluR-B
  • Glur-2
  • Glur2
  • glutamate receptor, ionotropic, AMPA 2
  • glutamate receptor, ionotropic, AMPA2 (alpha 2)
  • GRIA2
  • Gria2
  • gria2
Epitop
AA 652-807
54
20
11
7
7
6
5
3
3
2
2
2
2
2
1
1
1
1
1
1
1
Reaktivität
Human
153
131
95
20
18
13
9
7
7
7
6
4
4
4
3
2
2
1
1
Wirt
Maus
137
52
1
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser GRIA2 Antikörper ist unkonjugiert
6
4
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Flow Cytometry (FACS), ELISA, Western Blotting (WB)
161
59
48
25
24
24
13
8
8
3
3
2
1
1
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
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Immunogen Purified recombinant fragment of human GRIA2 (AA 652-807) expressed in E. Coli.
Klon 7G6
Isotyp IgG1
Reinigung Purified
Andere Bezeichnung GRIA2 (GRIA2 Antibody Abstract)
Hintergrund Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing (Q/R and R/G), which is thought to render the channels impermeable to Ca(2+), and to affect the kinetic aspects of these channels in rat brain. Alternative splicing, resulting in transcript variants encoding different isoforms (flip and flop), has been noted for this gene.
Molekulargewicht 98.8 kDa
Gen-ID 29627
HGNC 29627
Pathways PI3K-Akt Signalweg
Applikationshinweise ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Buffer PBS with 0.05 % sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C,-20 °C
Informationen zur Lagerung 4°C, -20°C for long term storage
Bilder des Herstellers
ELISA image for anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 652-807) antibody (ABIN969524) Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 n...
Flow Cytometry (FACS) image for anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 652-807) antibody (ABIN969524) Figure 2: Flow cytometric analysis of SK-N-SH cells using GRIA2 mouse mAb (green) and...
Western Blotting (WB) image for anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 652-807) antibody (ABIN969524) Figure 3: Western blot analysis using GRIA2 mouse mAb against HeLa (1) cell lysate.
Western Blotting (WB) image for anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 652-807) antibody (ABIN969524) Figure 4: Western blot analysis using GRIA2 mAb against human GRIA2 recombinant prote...
Western Blotting (WB) image for anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 652-807) antibody (ABIN969524) Figure 5: Western blot analysis using GRIA2 mAb against HEK293 (1) and GRIA2 (AA: 652...
Produkt verwendet in: Yu, Wu, Fu, Cheng, Yang, Chen, Long, Chen, Wang: "Aging-related alterations in the expression and distribution of GluR2 and PICK1 in the rat hippocampus." in: Neuroscience letters, Vol. 497, Issue 1, pp. 42-5, 2011 (PubMed).

Shen, Jin: "[GluR2 expression in the developing rat inferior colliculus and the relationship with development of synapse]." in: Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, Vol. 24, Issue 4, pp. 173-6, 2010 (PubMed).

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