DAXX Antikörper
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- Target Alle DAXX Antikörper anzeigen
- DAXX (Death-Domain Associated Protein (DAXX))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser DAXX Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human DAXX expressed in E. coli.
- Klon
- 7A11
- Isotyp
- IgG1
- Top Product
- Discover our top product DAXX Primärantikörper
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Antibody are purified by protein G affinity chromatography. Liquid in PBS containing 50 % glycerol and 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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- Target
- DAXX (Death-Domain Associated Protein (DAXX))
- Andere Bezeichnung
- DAXX (DAXX Produkte)
- Synonyme
- BING2 antikoerper, DAP6 antikoerper, EAP1 antikoerper, LOC100226911 antikoerper, daxx antikoerper, si:dz179b20.7 antikoerper, wu:fd15c03 antikoerper, death domain associated protein antikoerper, Fas death domain-associated protein antikoerper, 28S ribosomal protein S29, mitochondrial antikoerper, death-domain associated protein antikoerper, death-associated protein 6 L homeolog antikoerper, DAXX antikoerper, Daxx antikoerper, LOC100226911 antikoerper, daxx.L antikoerper, daxx antikoerper
- Hintergrund
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Description: DAXX (death-domain associated protein), it is a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.
Aliases: DAP6, EAP1, BING2
- Molekulargewicht
- 81 kDa
- Gen-ID
- 1616
- HGNC
- 1616
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
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