Lipase A Antikörper

Produktnummer ABIN969484

Produktdetails anti-Lipase A Antikörper

Target: Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Lipase A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: purified

Immunogen: Purified recombinant fragment of LAL expressed in E. coli.

Klon: 9G7F12

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-Lipase A Antikörper (ABIN969484)

Drebber, Andersen, Kasper, Lohse, Stolte, Dienes: "Severe chronic diarrhea and weight loss in cholesteryl ester storage disease: a case report." in: World journal of gastroenterology : WJG, Vol. 11, Issue 15, pp. 2364-6, (2005) (PubMed).

Boldrini, Devito, Biselli, Filocamo, Bosman: "Wolman disease and cholesteryl ester storage disease diagnosed by histological and ultrastructural examination of intestinal and liver biopsy." in: Pathology, research and practice, Vol. 200, Issue 3, pp. 231-40, (2004) (PubMed).

Details zu Lipase A

Target: Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))

Andere Bezeichnung: LAL (LIPA Produkte)

Synonyme: cesd antikoerper, lal antikoerper, LIPA antikoerper, CESD antikoerper, LAL antikoerper, Chole antikoerper, Chole2 antikoerper, Lip1 antikoerper, AA960673 antikoerper, Lal antikoerper, Lip-1 antikoerper, lipase A, lysosomal acid type antikoerper, lipase A, lysosomal acid, cholesterol esterase antikoerper, lipase A, lysosomal acid, cholesterol esterase L homeolog antikoerper, lysosomal acid lipase A antikoerper, LIPA antikoerper, lipa antikoerper, lipa.L antikoerper, Lipa antikoerper

Hintergrund:

Description: Lysosomal acid lipase (LAL), with 378-amino acid protein( 43-54 kDa), functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides which are taken up by receptor-mediated endocytosis. An inherited deficiency or low activity of human lysosomal acid lipase results in the intralysosomal storage of the respective lipid substrates. So it is also responsible for the rare conditions of Wolman disease and cholesteryl ester storage disease (CESD). As the enzyme is synthesized by all nucleated cells, lipid-laden cells are found in all organs, particularly in liver, spleen, the adrenal and the hemopoietic system, and in the intestine as well as in the lymph nodes, lungs, testes, and ovaries.

Aliases: LAL, CESD, LIPA

Gen-ID: 3988

HGNC: 3988