Osteoprotegerin Antikörper
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- Target Alle Osteoprotegerin (TNFRSF11B) Antikörper anzeigen
- Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Osteoprotegerin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human TNFRSF11B expressed in E. coli.
- Klon
- 5G2
- Isotyp
- IgG1
- Top Product
- Discover our top product TNFRSF11B Primärantikörper
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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A single-nucleotide polymorphism in the gene encoding osteoprotegerin is associated with diastolic blood pressure in older men." in: American journal of hypertension, Vol. 22, Issue 11, pp. 1167-70, (2009) (PubMed).
: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).
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A single-nucleotide polymorphism in the gene encoding osteoprotegerin is associated with diastolic blood pressure in older men." in: American journal of hypertension, Vol. 22, Issue 11, pp. 1167-70, (2009) (PubMed).
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- Target
- Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
- Andere Bezeichnung
- TNFRSF11B (TNFRSF11B Produkte)
- Synonyme
- CD254 antikoerper, ODF antikoerper, OPGL antikoerper, OPTB2 antikoerper, RANKL antikoerper, TRANCE antikoerper, hRANKL2 antikoerper, sOdf antikoerper, OCIF antikoerper, OPG antikoerper, TR1 antikoerper, Opg antikoerper, ocif antikoerper, opg antikoerper, tr1 antikoerper, TNF superfamily member 11 antikoerper, TNF receptor superfamily member 11b antikoerper, tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) antikoerper, TNF receptor superfamily member 11B antikoerper, tumor necrosis factor receptor superfamily member 11b S homeolog antikoerper, tumor necrosis factor receptor superfamily, member 11b antikoerper, TNFSF11 antikoerper, TNFRSF11B antikoerper, Tnfrsf11b antikoerper, tnfrsf11b.S antikoerper
- Substanzklasse
- Chemical
- Hintergrund
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Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
Aliases: OPG, TR1, OCIF, MGC29565, TNFRSF11B
- Molekulargewicht
- 60 kDa
- Gen-ID
- 4982
- HGNC
- 4982
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