Synaptophysin Antikörper

Produktnummer ABIN969428

Produktdetails anti-Synaptophysin Antikörper

Target: Synaptophysin (SYP)

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Synaptophysin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Aufreinigung: purified

Immunogen: Purified recombinant fragment of SYP expressed in E. coli.

Klon: 7H12

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-Synaptophysin Antikörper (ABIN969428)

Gulubova, Vlaykova: "Chromogranin A-, serotonin-, synaptophysin- and vascular endothelial growth factor-positive endocrine cells and the prognosis of colorectal cancer: an immunohistochemical and ultrastructural study." in: Journal of gastroenterology and hepatology, Vol. 23, Issue 10, pp. 1574-85, (2009) (PubMed).

Sterlacci, Fiegl, Hilbe, Auberger, Mikuz, Tzankov: "Clinical relevance of neuroendocrine differentiation in non-small cell lung cancer assessed by immunohistochemistry: a retrospective study on 405 surgically resected cases." in: Virchows Archiv : an international journal of pathology, Vol. 455, Issue 2, pp. 125-32, (2009) (PubMed).

Xu, Dai, Xiang, Zhao, Ruan, Cheng, Zheng, Shu: "Nutritional factors in relation to endometrial cancer: a report from a population-based case-control study in Shanghai, China." in: International journal of cancer. Journal international du cancer, Vol. 120, Issue 8, pp. 1776-81, (2007) (PubMed).

Details zu Synaptophysin

Target: Synaptophysin (SYP)

Andere Bezeichnung: SYP (SYP Produkte)

Synonyme: syp-B antikoerper, xsypii antikoerper, MGC86267 antikoerper, MRXSYP antikoerper, A230093K24Rik antikoerper, AI848995 antikoerper, Syn antikoerper, p38 antikoerper, Syp1 antikoerper, mrxsyp antikoerper, syp antikoerper, xsypi antikoerper, synaptophysin S homeolog antikoerper, synaptophysin antikoerper, synaptophysin L homeolog antikoerper, synaptophysin a antikoerper, syp.S antikoerper, SYP antikoerper, syp antikoerper, Syp antikoerper, syp.L antikoerper, sypa antikoerper

Hintergrund:

Description: Synaptophysin (p38) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells.Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore. Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases. Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex.

Aliases: MRXSYP, SYP

Molekulargewicht: 33.8 kDa

Gen-ID: 6855

HGNC: 6855

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity