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STAT6 Antikörper

STAT6 Reaktivität: Human, Maus, Ratte, Affe WB, ELISA, ICC Wirt: Maus Monoclonal 7D3 unconjugated
Produktnummer ABIN969423
  • Target Alle STAT6 Antikörper anzeigen
    STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))
    Reaktivität
    • 141
    • 78
    • 62
    • 10
    • 9
    • 9
    • 7
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Affe
    Wirt
    • 113
    • 31
    • 4
    • 1
    Maus
    Klonalität
    • 101
    • 47
    Monoklonal
    Konjugat
    • 82
    • 7
    • 7
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser STAT6 Antikörper ist unkonjugiert
    Applikation
    • 74
    • 43
    • 43
    • 27
    • 26
    • 26
    • 25
    • 19
    • 19
    • 10
    • 9
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human STAT6 expressed in E. coli.
    Klon
    7D3
    Isotyp
    IgG1
    Top Product
    Discover our top product STAT6 Primärantikörper
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Ikeuchi, Kobayashi, Arakawa, Suzuki, Tamra, Morikawa: "Polymorphisms in interleukin-4-related genes in patients with minimal change nephrotic syndrome." in: Pediatric nephrology (Berlin, Germany), Vol. 24, Issue 3, pp. 489-95, (2009) (PubMed).

    Inomata, Into, Nakashima, Noguchi, Matsushita: "IL-4 alters expression patterns of storage components of vascular endothelial cell-specific granules through STAT6- and SOCS-1-dependent mechanisms." in: Molecular immunology, Vol. 46, Issue 10, pp. 2080-9, (2009) (PubMed).

    Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

  • Target
    STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))
    Andere Bezeichnung
    STAT6 (STAT6 Produkte)
    Synonyme
    D12S1644 antikoerper, IL-4-STAT antikoerper, STAT6B antikoerper, STAT6C antikoerper, signal transducer and activator of transcription 6 antikoerper, signal transducer and activator of transcription 6-like antikoerper, STAT6 antikoerper, Stat6 antikoerper, LOC100859543 antikoerper
    Hintergrund

    Description: STAT6 protein is a transcription factor activated by cytokines, particularly interleukin 4 and IL 13. (STAT6-/-) were found to be deficient in IL 4 mediated functions including Th2 helper T cell differentiation, expression of cell surface markers, T cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL 4 mediated proliferation. STAT6 mRNA has been detected in peripheral bloodlymphocytes, colon, intestine, ovary, prostate,thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response.

    Aliases: STAT6B, STAT6C, D12S1644, IL-4-STAT, STAT6

    Molekulargewicht
    94 kDa
    Gen-ID
    6778
    HGNC
    6778
    Pathways
    JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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