SMAD5 Antikörper (SMAD, Mothers Against DPP Homolog 5)

Details for Product anti-SMAD5 Antibody No. ABIN969404, Anbieter: Anmelden zum Anzeigen
Antigen
  • SBN
  • fb67b04
  • mad
  • madh5
  • sb:cb400
  • smd5
  • wu:fb67b04
  • XSmad4alpha
  • dpc4
  • jip
  • jv5-1
  • madh4
  • smad10
  • smad5
  • xsmad4
  • DWFC
  • JV5-1
  • MADH5
  • 1110051M15Rik
  • AI451355
  • Dwf-C
  • Madh5
  • MusMLP
  • SMAD5
  • DKFZp468M0619
  • SMAD family member 5
  • MAD homolog 5 (Drosophila)
  • SMAD family member 4, gene 2
  • SMAD5
  • smad5
  • smad4.2-b
  • Smad5
Reaktivität
Human, Ratte (Rattus)
108
47
39
8
7
6
6
5
5
4
3
2
2
1
Wirt
Maus
71
38
1
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser SMAD5 Antikörper ist unkonjugiert
3
3
3
3
3
3
Applikation
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
105
56
29
24
18
17
10
3
2
1
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen Purified recombinant fragment of human SMAD5 expressed in E. Coli.
Klon 3H9
Isotyp IgG1
Reinigung Ascites
Andere Bezeichnung SMAD5 (SMAD5 Antibody Abstract)
Hintergrund Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). SMAD5 is required for normal development of the cardiovascular system in vivo, lack of the SMAD5 gene results in apoptosis of cardiac myocytes. 3 Upregulation of SMAD5 has been reported to mediate apoptosis of gastric epithelial cells induced by Helicobacter pylori infection. Tissue specificity: Ubiquitous.
Molekulargewicht 52 kDa
Gen-ID 4090
HGNC 4090
Forschungsgebiet Organogenesis, Signaling, Transcription Factors
Applikationshinweise ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C,-20 °C
Informationen zur Lagerung 4°C, -20°C for long term storage
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-SMAD, Mothers Against DPP Homolog 5 (SMAD5) antibody (ABIN969404) Figure 1: Flow cytometric analysis of Jurkat cells using SMAD5 mouse mAb (green) and ...
Immunocytochemistry (ICC) image for anti-SMAD, Mothers Against DPP Homolog 5 (SMAD5) antibody (ABIN969404) Figure 2: Immunofluorescence analysis of NTERA-2 cells using SMAD5 mouse mAb (green) ...
Immunohistochemistry (IHC) image for anti-SMAD, Mothers Against DPP Homolog 5 (SMAD5) antibody (ABIN969404) Figure 3: Immunohistochemical analysis of paraffin-embedded brain tissues (left) and ...
Western Blotting (WB) image for anti-SMAD, Mothers Against DPP Homolog 5 (SMAD5) antibody (ABIN969404) Figure 4: Western blot analysis using SMAD5 mouse mAb against Hela (1), SK-N-SH (2), ...
Produkt verwendet in: Chang, Chang, Lee, Lee, Yeh, Yeh, Cheng, Chien, Chiu: "Tumor cell cycle arrest induced by shear stress: Roles of integrins and Smad." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 10, pp. 3927-32, 2008 (PubMed).

Monzen, Ito, Naito, Kasai, Hiroi, Hayashi, Shiojima, Yamazaki, Miyazono, Asashima, Nagai, Komuro: "A crucial role of a high mobility group protein HMGA2 in cardiogenesis." in: Nature cell biology, Vol. 10, Issue 5, pp. 567-74, 2008 (PubMed).

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