RPS6KA3 Antikörper

Produktnummer ABIN969386

Produktdetails anti-RPS6KA3 Antikörper

Target: RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RPS6KA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human RSK2 expressed in E. coli.

Klon: 4-00E-10

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-RPS6KA3 Antikörper (ABIN969386)

Dehan, Bassermann, Guardavaccaro, Vasiliver-Shamis, Cohen, Lowes, Dustin, Huang, Taunton, Pagano: "betaTrCP- and Rsk1/2-mediated degradation of BimEL inhibits apoptosis." in: Molecular cell, Vol. 33, Issue 1, pp. 109-16, (2009) (PubMed).

Cho, Yao, Pugliese, Malakhova, Bode, Dong: "A regulatory mechanism for RSK2 NH(2)-terminal kinase activity." in: Cancer research, Vol. 69, Issue 10, pp. 4398-406, (2009) (PubMed).

Details zu RPS6KA3

Target: RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))

Andere Bezeichnung: RSK2 (RPS6KA3 Produkte)

Synonyme: HU-1 antikoerper, MAPKAPK1A antikoerper, RSK antikoerper, RSK1 antikoerper, CLS antikoerper, HU-3 antikoerper, ISPK-1 antikoerper, MAPKAPK1B antikoerper, MRX19 antikoerper, RSK2 antikoerper, S6K-alpha3 antikoerper, p90-RSK2 antikoerper, pp90RSK2 antikoerper, MPK-9 antikoerper, Rsk2 antikoerper, RGD1563860 antikoerper, id:ibd1103 antikoerper, rps6ka3 antikoerper, si:ch211-114c12.12 antikoerper, wu:fk86e02 antikoerper, zgc:56006 antikoerper, zgc:158386 antikoerper, ribosomal protein S6 kinase A1 antikoerper, ribosomal protein S6 kinase A3 antikoerper, ribosomal protein S6 kinase polypeptide 3 antikoerper, ribosomal protein S6 kinase a, polypeptide 3a antikoerper, ribosomal protein S6 kinase, polypeptide 3b antikoerper, RPS6KA1 antikoerper, RPS6KA3 antikoerper, Rps6ka3 antikoerper, rps6ka3a antikoerper, rps6ka3b antikoerper

Hintergrund:

Description: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS).

Aliases: RPS6KA3, CLS, RSK, HU-3, RSK2, MRX19, ISPK-1, p90-RSK2, pp90RSK2, MAPKAPK1B, S6K-alpha3

Molekulargewicht: 80 kDa

Gen-ID: 6197

HGNC: 6197

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades