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Progesterone Receptor Antikörper (AA 730-871)

PGR Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 8A11H1 unconjugated
Produktnummer ABIN969352
  • Target Alle Progesterone Receptor (PGR) Antikörper anzeigen
    Progesterone Receptor (PGR)
    Bindungsspezifität
    • 16
    • 16
    • 15
    • 14
    • 13
    • 12
    • 11
    • 10
    • 9
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 730-871
    Reaktivität
    • 239
    • 42
    • 38
    • 16
    • 15
    • 8
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 182
    • 59
    • 1
    • 1
    Maus
    Klonalität
    • 176
    • 67
    Monoklonal
    Konjugat
    • 120
    • 21
    • 11
    • 11
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser Progesterone Receptor Antikörper ist unkonjugiert
    Applikation
    • 176
    • 89
    • 57
    • 32
    • 29
    • 26
    • 26
    • 25
    • 18
    • 18
    • 17
    • 12
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of PGR (aa730-871) expressed in E. coli.
    Klon
    8A11H1
    Isotyp
    IgG1
    Top Product
    Discover our top product PGR Primärantikörper
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • LEplattenier, Lai, van den Ham, Mol, van Sluijs, Teske: "Regulation of COX-2 expression in canine prostate carcinoma: increased COX-2 expression is not related to inflammation." in: Journal of veterinary internal medicine / American College of Veterinary Internal Medicine, Vol. 21, Issue 4, pp. 776-82, (2007) (PubMed).

    Yin, Lin, Cheng, Marsh, Utsunomiya, Ishikawa, Xue, Reierstad, Innes, Thung, Kim, Xu, Bulun: "Progesterone receptor regulates Bcl-2 gene expression through direct binding to its promoter region in uterine leiomyoma cells." in: The Journal of clinical endocrinology and metabolism, Vol. 92, Issue 11, pp. 4459-66, (2007) (PubMed).

    Saito, Ito, Nagase, Suzuki, Akahira, Okamura, Yaegashi, Sasano: "Progesterone receptor isoforms as a prognostic marker in human endometrial carcinoma." in: Cancer science, Vol. 97, Issue 12, pp. 1308-14, (2006) (PubMed).

    Tung, Abdel-Hafiz, Shen, Harvell, Nitao, Richer, Sartorius, Takimoto, Horwitz: "Progesterone receptors (PR)-B and -A regulate transcription by different mechanisms: AF-3 exerts regulatory control over coactivator binding to PR-B." in: Molecular endocrinology (Baltimore, Md.), Vol. 20, Issue 11, pp. 2656-70, (2006) (PubMed).

    Buser, Gass-Handel, Wyszomierski, Doppler, Leonhardt, Schaack, Rosen, Watkin, Anderson, Edwards: "Progesterone receptor repression of prolactin/signal transducer and activator of transcription 5-mediated transcription of the beta-casein gene in mammary epithelial cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 21, Issue 1, pp. 106-25, (2006) (PubMed).

  • Target
    Progesterone Receptor (PGR)
    Andere Bezeichnung
    PGR (PGR Produkte)
    Synonyme
    NR3C3 antikoerper, PR antikoerper, 9930019P03Rik antikoerper, BB114106 antikoerper, ENSMUSG00000074510 antikoerper, PR-A antikoerper, PR-B antikoerper, XPR-1 antikoerper, pgr antikoerper, xpr-2 antikoerper, LOC443444 antikoerper, PGR antikoerper, pg antikoerper, pr antikoerper, gb:dq017620 antikoerper, progesterone receptor antikoerper, progesterone receptor L homeolog antikoerper, PGR antikoerper, Pgr antikoerper, pgr.L antikoerper, pgr antikoerper
    Hintergrund

    Description: PGR: progesterone receptor. This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform B has not been clearly determined.

    Aliases: PR, NR3C3, PGR

    Gen-ID
    5241
    HGNC
    5241
    Pathways
    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
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