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PEG10 Antikörper (AA 1-120)

PEG10 Reaktivität: Human WB, ELISA, IHC, ICC Wirt: Maus Monoclonal 1B1C4 unconjugated
Produktnummer ABIN969348
  • Target Alle PEG10 Antikörper anzeigen
    PEG10 (Paternally Expressed 10 (PEG10))
    Bindungsspezifität
    • 15
    • 15
    • 9
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-120
    Reaktivität
    • 51
    • 21
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 44
    • 7
    Maus
    Klonalität
    • 46
    • 5
    Monoklonal
    Konjugat
    • 21
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PEG10 Antikörper ist unkonjugiert
    Applikation
    • 46
    • 27
    • 14
    • 13
    • 13
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of PEG10 (aa1-120) expressed in E. coli.
    Klon
    1B1C4
    Isotyp
    IgG1
    Top Product
    Discover our top product PEG10 Primärantikörper
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Kochetov, Ahmad, Ivanisenko, Volkova, Kolchanov, Sarai: "uORFs, reinitiation and alternative translation start sites in human mRNAs." in: FEBS letters, Vol. 582, Issue 9, pp. 1293-7, (2008) (PubMed).

    Wang, Xiao, Hu, Chen, Liu, Hu: "PEG10 directly regulated by E2Fs might have a role in the development of hepatocellular carcinoma." in: FEBS letters, Vol. 582, Issue 18, pp. 2793-8, (2008) (PubMed).

    Jie, Lang, Jian, Chaoqun, Dehua, Yi, Yanping, Luokun, Qiuping, Hui, Feili, Boquan, Youxin, Jinquan: "Androgen activates PEG10 to promote carcinogenesis in hepatic cancer cells." in: Oncogene, Vol. 26, Issue 39, pp. 5741-51, (2007) (PubMed).

  • Target
    PEG10 (Paternally Expressed 10 (PEG10))
    Andere Bezeichnung
    PEG10 (PEG10 Produkte)
    Synonyme
    EDR antikoerper, HB-1 antikoerper, MEF3L antikoerper, Mar2 antikoerper, Mart2 antikoerper, RGAG3 antikoerper, AA407948 antikoerper, Edr antikoerper, MyEF-3 antikoerper, paternally expressed 10 antikoerper, PEG10 antikoerper, Peg10 antikoerper
    Hintergrund

    Description: PEG10: paternally expressed 10. This gene includes two overlapping reading frames of the same transcript encoding distinct isoforms. The shorter isoform has a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons, and it functions in part by interacting with members of the TGF-beta receptor family. The longer isoform has the active-site DSG consensus sequence of the protease domain of pol proteins. The longer isoform is the result of -1 translational frameshifting that is also seen in some retroviruses. Expression of these two isoforms only comes from the paternal allele due to imprinting. Increased gene expression (as observed by an increase in mRNA levels) is associated with hepatocellular carcinomas.

    Aliases: Edr, HB-1, Mar2, MEF3L, Mart2, RGAG3, KIAA1051

    Gen-ID
    23089
    HGNC
    23089
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