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PAX8 Antikörper

PAX8 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 2D4 unconjugated
Produktnummer ABIN969343
  • Target Alle PAX8 Antikörper anzeigen
    PAX8 (Paired Box 8 (PAX8))
    Reaktivität
    • 111
    • 48
    • 45
    • 20
    • 20
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    Human
    Wirt
    • 73
    • 37
    • 1
    Maus
    Klonalität
    • 56
    • 55
    Monoklonal
    Konjugat
    • 62
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PAX8 Antikörper ist unkonjugiert
    Applikation
    • 87
    • 35
    • 31
    • 31
    • 26
    • 17
    • 16
    • 12
    • 11
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human PAX8 expressed in E. coli.
    Klon
    2D4
    Isotyp
    IgG1
    Top Product
    Discover our top product PAX8 Primärantikörper
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • McKnight, Cohen, Siddiqui: "Utility of paired box gene 8 (PAX8) expression in fluid and fine-needle aspiration cytology: an immunohistochemical study of metastatic ovarian serous carcinoma." in: Cancer cytopathology, Vol. 118, Issue 5, pp. 298-302, (2010) (PubMed).

  • Target
    PAX8 (Paired Box 8 (PAX8))
    Andere Bezeichnung
    PAX8 (PAX8 Produkte)
    Synonyme
    PAX8 antikoerper, XPax-8 antikoerper, XPax8 antikoerper, pax-8 antikoerper, PAX-8 antikoerper, Pax-8 antikoerper, paired box 8 antikoerper, paired box 8 L homeolog antikoerper, PAX8 antikoerper, pax8 antikoerper, Pax8 antikoerper, pax8.L antikoerper
    Hintergrund

    Description: This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas.Tissue specificity: Expressed in the excretory system, thyroid gland and Wilms tumors.ABCAM: This protein is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain, an octapeptide, and a paired-type homeodomain. This family plays critical roles during fetal development and cancer growth. The specific function of the PAX8 is unknown but it may involve kidney cell differentiation, thyroid development, or thyroid dysgenesis. Alternative splicing in the gene by inclusion or exclusion of exons 7 and/or 8 has produced several known products but the biological significance of the variants is unknown. Several other splice variants have been proposed but the full nature of these products has not been described. Pax8 is also a marker of otic progenitor cells.

    Aliases: PAX8

    Molekulargewicht
    60 kDa
    Gen-ID
    7846
    HGNC
    7846
    Pathways
    Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Stem Cell Maintenance, Tube Formation
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