Glucocorticoid Receptor Antikörper
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- Target Alle Glucocorticoid Receptor (NR3C1) Antikörper anzeigen
- Glucocorticoid Receptor (NR3C1) (Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Glucocorticoid Receptor Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human NR3C1 expressed in E. coli.
- Klon
- 6-00E-06
- Isotyp
- IgG1
- Top Product
- Discover our top product NR3C1 Primärantikörper
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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A novel point mutation in the amino terminal domain of the human glucocorticoid receptor (hGR) gene enhancing hGR-mediated gene expression." in: The Journal of clinical endocrinology and metabolism, Vol. 93, Issue 12, pp. 4963-8, (2008) (PubMed).
: "Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses." in: Epigenetics, Vol. 3, Issue 2, pp. 97-106, (2008) (PubMed).
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A novel point mutation in the amino terminal domain of the human glucocorticoid receptor (hGR) gene enhancing hGR-mediated gene expression." in: The Journal of clinical endocrinology and metabolism, Vol. 93, Issue 12, pp. 4963-8, (2008) (PubMed).
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- Target
- Glucocorticoid Receptor (NR3C1) (Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1))
- Andere Bezeichnung
- NR3C1 (NR3C1 Produkte)
- Synonyme
- GR antikoerper, gcr antikoerper, grl antikoerper, xGR antikoerper, gccr antikoerper, gr antikoerper, zgc:113038 antikoerper, NR3C1 antikoerper, GCL antikoerper, LOC100302444 antikoerper, Gcr antikoerper, Grl antikoerper, Grl-1 antikoerper, Grl1 antikoerper, GRL antikoerper, GCCR antikoerper, GCR antikoerper, NO antikoerper, GR-A antikoerper, nr3c1 antikoerper, nuclear receptor subfamily 3 group C member 1 antikoerper, nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) antikoerper, nuclear receptor subfamily 3, group C, member 1 antikoerper, glucocorticoid receptor antikoerper, NR3C1 antikoerper, nr3c1 antikoerper, LOC100302444 antikoerper, Nr3c1 antikoerper
- Hintergrund
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Description: The protein encoded by this gene is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. Tissue specificity: Widely expressed. In the heart, detected in left and right atria, left and right ventricles, aorta, apex, intraventricular septum, and atrioventricular node as well as whole adult and fetal heart.
Aliases: GR, GCR, GRL, GCCR, NR3C1
- Molekulargewicht
- 86 kDa
- Gen-ID
- 2908
- HGNC
- 2908
- Pathways
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Regulation of Carbohydrate Metabolic Process
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