NCOR1 Antikörper (AA 1-192)

Produktnummer ABIN969310

Produktdetails anti-NCOR1 Antikörper

Target: NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

Bindungsspezifität: AA 1-192

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NCOR1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of NCOR1 (aa1-192) expressed in E. coli.

Klon: 7A7A9

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-NCOR1 Antikörper (ABIN969310)

Atsumi, Tomita, Kiyoi, Naoe: "Histone deacetylase 3 (HDAC3) is recruited to target promoters by PML-RARalpha as a component of the N-CoR co-repressor complex to repress transcription in vivo." in: Biochemical and biophysical research communications, Vol. 345, Issue 4, pp. 1471-80, (2006) (PubMed).

Zhang, Yoon, Wong: "JMJD2A is a novel N-CoR-interacting protein and is involved in repression of the human transcription factor achaete scute-like homologue 2 (ASCL2/Hash2)." in: Molecular and cellular biology, Vol. 25, Issue 15, pp. 6404-14, (2005) (PubMed).

Details zu NCOR1

Target: NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

Andere Bezeichnung: NCOR1 (NCOR1 Produkte)

Synonyme: ncor antikoerper, zgc:56355 antikoerper, 5730405M06Rik antikoerper, A230020K14Rik antikoerper, N-CoR antikoerper, RIP13 antikoerper, Rxrip13 antikoerper, mKIAA1047 antikoerper, N-CoR1 antikoerper, TRAC1 antikoerper, hN-CoR antikoerper, nuclear receptor corepressor 1 antikoerper, nuclear receptor co-repressor 1 antikoerper, nuclear receptor corepressor 1 pseudogene antikoerper, nuclear receptor corepressor 1 S homeolog antikoerper, ncor1 antikoerper, NCOR1 antikoerper, CpipJ_CPIJ002507 antikoerper, LOC100343278 antikoerper, Ncor1 antikoerper, ncor1.S antikoerper

Hintergrund:

Description: NCOR1: Nuclear receptor co-repressor 1. This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined.

Aliases: N-CoR, TRAC1, hN-CoR

Gen-ID: 9611

HGNC: 9611

Pathways: Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process