MSH6 Antikörper (MutS Homolog 6 (E. Coli))

Details for Product anti-MSH6 Antibody No. ABIN969293, Anbieter: Anmelden zum Anzeigen
Antigen
  • cb326
  • wu:fb36c12
  • LOC100227810
  • GTBP
  • GTMBP
  • HNPCC5
  • HSAP
  • p160
  • AU044881
  • AW550279
  • Gtmbp
  • mutS homolog 6 (E. coli)
  • LOC100360342
  • msh6
  • Msh6
  • MSH6
  • LOC100227810
Reaktivität
Human
151
51
40
9
7
2
1
1
1
1
1
Wirt
Maus
78
61
12
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser MSH6 Antikörper ist unkonjugiert
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
106
51
45
41
38
13
13
11
8
6
5
4
4
3
2
1
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
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Immunogen Purified recombinant fragment of human MSH6 expressed in E. Coli.
Klon 3-00E-01
Isotyp IgG2a
Reinigung Ascites
Andere Bezeichnung MSH6 (MSH6 Antibody Abstract)
Hintergrund This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer.
Molekulargewicht 160 kDa
Gen-ID 2956
HGNC 2956
Forschungsgebiet Chromatin and Nuclear Signaling, DNA/RNA
Pathways DNA Reparatur, Chromatin Binding, Production of Molecular Mediator of Immune Response
Applikationshinweise ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C,-20 °C
Informationen zur Lagerung 4°C, -20°C for long term storage
Bilder des Herstellers
ELISA image for anti-MutS Homolog 6 (E. Coli) (MSH6) antibody (ABIN969293) Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 n...
Flow Cytometry (FACS) image for anti-MutS Homolog 6 (E. Coli) (MSH6) antibody (ABIN969293) Figure 2: Flow cytometric analysis of MCF-7 cells using MSH6 mouse mAb (green) and ne...
Immunocytochemistry (ICC) image for anti-MutS Homolog 6 (E. Coli) (MSH6) antibody (ABIN969293) Figure 3: Immunofluorescence analysis of Hela cells using MSH6 mouse mAb (green) . Bl...
Immunohistochemistry (IHC) image for anti-MutS Homolog 6 (E. Coli) (MSH6) antibody (ABIN969293) Figure 4: Immunohistochemical analysis of paraffin-embedded rectum cancer tissues usi...
Immunohistochemistry (IHC) image for anti-MutS Homolog 6 (E. Coli) (MSH6) antibody (ABIN969293) Figure 5: Immunohistochemical analysis of paraffin-embedded colon cancer tissues usin...
Western Blotting (WB) image for anti-MutS Homolog 6 (E. Coli) (MSH6) antibody (ABIN969293) Figure 6: Western blot analysis using MSH6 mouse mAb against HEK293 (1), HCT116 (2), ...
Western Blotting (WB) image for anti-MutS Homolog 6 (E. Coli) (MSH6) antibody (ABIN969293) Figure 7: Western blot analysis using MSH6 mAb against human MSH6 (AA: 217-395) recom...
Produkt verwendet in: Grindedal, Møller, Eeles, Stormorken, Bowitz-Lothe, Landrø, Clark, Kvåle, Shanley, Maehle: "Germ-line mutations in mismatch repair genes associated with prostate cancer." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 9, pp. 2460-7, 2009 (PubMed).

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