MSH6 Antikörper (MutS Homolog 6 (E. Coli))

Details for Product anti-MSH6 Antibody No. ABIN969292, Anbieter: Anmelden zum Anzeigen
Antigen
  • cb326
  • wu:fb36c12
  • LOC100227810
  • GTBP
  • GTMBP
  • HNPCC5
  • HSAP
  • p160
  • AU044881
  • AW550279
  • Gtmbp
  • mutS homolog 6 (E. coli)
  • LOC100360342
  • msh6
  • Msh6
  • MSH6
  • LOC100227810
Reaktivität
Human
151
51
40
9
7
2
1
1
1
1
1
Wirt
Maus
78
61
12
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser MSH6 Antikörper ist unkonjugiert
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
106
51
45
42
38
13
13
12
9
6
5
4
4
3
2
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen Purified recombinant fragment of human MSH6 expressed in E. Coli.
Klon 5B11
Isotyp IgG1
Reinigung Ascites
Andere Bezeichnung MSH6 (MSH6 Antibody Abstract)
Hintergrund This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer.
Molekulargewicht 160 kDa
Gen-ID 2956
HGNC 2956
Forschungsgebiet Chromatin and Nuclear Signaling, DNA/RNA
Pathways DNA Reparatur, Chromatin Binding, Production of Molecular Mediator of Immune Response
Applikationshinweise ELISA: 1:10000, WB: 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C,-20 °C
Informationen zur Lagerung 4°C, -20°C for long term storage
Bilder des Herstellers
ELISA image for anti-MutS Homolog 6 (E. Coli) (MSH6) antibody (ABIN969292) Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 n...
Western Blotting (WB) image for anti-MutS Homolog 6 (E. Coli) (MSH6) antibody (ABIN969292) Figure 2: Western blot analysis using MSH6 mouse mAb against MCF-7 (1), HEK293 (2), a...
Western Blotting (WB) image for anti-MutS Homolog 6 (E. Coli) (MSH6) antibody (ABIN969292) Figure 3: Western blot analysis using MSH6 mAb against human MSH6 (AA: 217-395) recom...
Produkt verwendet in: Becker, Creagh, ONeill: "Rab39a binds caspase-1 and is required for caspase-1-dependent interleukin-1beta secretion." in: The Journal of biological chemistry, Vol. 284, Issue 50, pp. 34531-7, 2009 (PubMed).

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