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MSH6 Antikörper

MSH6 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 5B11 unconjugated
Produktnummer ABIN969292
  • Target Alle MSH6 Antikörper anzeigen
    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
    Reaktivität
    • 81
    • 37
    • 31
    • 9
    • 5
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 59
    • 19
    • 3
    Maus
    Klonalität
    • 46
    • 35
    Monoklonal
    Konjugat
    • 49
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MSH6 Antikörper ist unkonjugiert
    Applikation
    • 56
    • 27
    • 25
    • 23
    • 14
    • 13
    • 12
    • 8
    • 8
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human MSH6 expressed in E. coli.
    Klon
    5B11
    Isotyp
    IgG1
    Top Product
    Discover our top product MSH6 Primärantikörper
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Becker, Creagh, ONeill: "Rab39a binds caspase-1 and is required for caspase-1-dependent interleukin-1beta secretion." in: The Journal of biological chemistry, Vol. 284, Issue 50, pp. 34531-7, (2009) (PubMed).

  • Target
    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
    Andere Bezeichnung
    MSH6 (MSH6 Produkte)
    Synonyme
    GTBP antikoerper, GTMBP antikoerper, HNPCC5 antikoerper, HSAP antikoerper, p160 antikoerper, cb326 antikoerper, wu:fb36c12 antikoerper, LOC100227810 antikoerper, AU044881 antikoerper, AW550279 antikoerper, Gtmbp antikoerper, mutS homolog 6 antikoerper, mutS homolog 6 (E. coli) antikoerper, DNA mismatch repair protein antikoerper, MSH6 antikoerper, msh6 antikoerper, Msh6 antikoerper
    Hintergrund

    Description: This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer. 

    Aliases: GTBP, HSAP, HNPCC5

    Molekulargewicht
    160 kDa
    Gen-ID
    2956
    HGNC
    2956
    Pathways
    DNA Reparatur, Chromatin Binding, Production of Molecular Mediator of Immune Response
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