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MAP4K4 Antikörper (AA 400-500)

MAP4K4 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 4H9E7 unconjugated
Produktnummer ABIN969274
  • Target Alle MAP4K4 Antikörper anzeigen
    MAP4K4 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4))
    Bindungsspezifität
    • 22
    • 10
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 400-500
    Reaktivität
    • 65
    • 18
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 62
    • 3
    Maus
    Klonalität
    • 61
    • 4
    Monoklonal
    Konjugat
    • 33
    • 5
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MAP4K4 Antikörper ist unkonjugiert
    Applikation
    • 35
    • 34
    • 15
    • 15
    • 10
    • 10
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of MAP4K4 (aa400-500) expressed in E. coli.
    Klon
    4H9E7
    Isotyp
    IgG1
    Top Product
    Discover our top product MAP4K4 Primärantikörper
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Bouzakri, Zierath: "MAP4K4 gene silencing in human skeletal muscle prevents tumor necrosis factor-alpha-induced insulin resistance." in: The Journal of biological chemistry, Vol. 282, Issue 11, pp. 7783-9, (2007) (PubMed).

    Poinat, De Arcangelis, Sookhareea, Zhu, Hedgecock, Labouesse, Georges-Labouesse: "A conserved interaction between beta1 integrin/PAT-3 and Nck-interacting kinase/MIG-15 that mediates commissural axon navigation in C. elegans." in: Current biology : CB, Vol. 12, Issue 8, pp. 622-31, (2002) (PubMed).

    Becker, Huynh-Do, Holland, Pawson, Daniel, Skolnik: "Nck-interacting Ste20 kinase couples Eph receptors to c-Jun N-terminal kinase and integrin activation." in: Molecular and cellular biology, Vol. 20, Issue 5, pp. 1537-45, (2000) (PubMed).

  • Target
    MAP4K4 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4))
    Andere Bezeichnung
    MAP4K4 (MAP4K4 Produkte)
    Synonyme
    FLH21957 antikoerper, HGK antikoerper, MEKKK4 antikoerper, NIK antikoerper, 9430080K19Rik antikoerper, AU043147 antikoerper, AU045934 antikoerper, AW046177 antikoerper, Nik antikoerper, mitogen-activated protein kinase kinase kinase kinase 4 antikoerper, MAP4K4 antikoerper, Map4k4 antikoerper
    Hintergrund

    Description: MAP4K4: mitogen-activated protein kinase kinase kinase kinase 4. The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified.

    Aliases: HGK, NIK

    Gen-ID
    9448
    HGNC
    9448
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