LSD1 Antikörper

Produktnummer ABIN969264

Produktdetails anti-LSD1 Antikörper

Target: LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))

Reaktivität: Human, Maus, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LSD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human LSD1 expressed in E. coli.

Klon: 1B2E5

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-LSD1 Antikörper (ABIN969264)

Shi, Matson, Lan, Iwase, Baba, Shi: "Regulation of LSD1 histone demethylase activity by its associated factors." in: Molecular cell, Vol. 19, Issue 6, pp. 857-64, (2005) (PubMed).

Metzger, Wissmann, Yin, Müller, Schneider, Peters, Günther, Buettner, Schüle: "LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription." in: Nature, Vol. 437, Issue 7057, pp. 436-9, (2005) (PubMed).

Details zu LSD1

Target: LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))

Andere Bezeichnung: LSD1/AOF2 (KDM1A Produkte)

Synonyme: AOF2 antikoerper, BHC110 antikoerper, KDM1 antikoerper, LSD1 antikoerper, 1810043O07Rik antikoerper, AA408884 antikoerper, Aof2 antikoerper, D4Ertd478e antikoerper, Kdm1 antikoerper, Lsd1 antikoerper, mKIAA0601 antikoerper, DKFZp459N2450 antikoerper, RGD1562975 antikoerper, aof2 antikoerper, kdm1 antikoerper, wu:fb82e06 antikoerper, wu:fc51a02 antikoerper, wu:fj36a05 antikoerper, wu:fj66b06 antikoerper, KDM1A antikoerper, lsd1 antikoerper, xLSD1 antikoerper, AtLSD1 antikoerper, F9F13.30 antikoerper, F9F13_30 antikoerper, LESION SIMULATING DISEASE antikoerper, LESION SIMULATING DISEASE 1 antikoerper, lysine demethylase 1A antikoerper, lysine (K)-specific demethylase 1A antikoerper, lysine (K)-specific demethylase 1a antikoerper, LSD1 zinc finger family protein antikoerper, KDM1A antikoerper, Kdm1a antikoerper, kdm1a antikoerper, LSD1 antikoerper

Hintergrund:

Description: The amine oxidase domain 2 (AOF2) gene encodes a nuclear protein (LSD1, ~95 kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex (es) on chromatin.

Aliases: KDM1, LSD1, AOF2

Molekulargewicht: 93 kDa

Gen-ID: 23028

HGNC: 23028

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling, Warburg Effekt