KSHVORF62 Antikörper

Produktnummer ABIN969255

Produktdetails

Target: KSHVORF62

Reaktivität: Human Herpesvirus 8 (HHV-8)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human KSHV ORF62 expressed in E. coli.

Klon: 5B7B6

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen

Holyfield: "Spit Tobacco Prevention Network (STOPN)." in: Texas nursing, Vol. 74, Issue 10, pp. 9, (2002) (PubMed).

Wu, Lo, Yu, Stoops, Forghani, Zhou: "Three-dimensional structure of the human herpesvirus 8 capsid." in: Journal of virology, Vol. 74, Issue 20, pp. 9646-54, (2000) (PubMed).

Nakamura, Oguri, Tabe, Igari: "[Epidemiological study on Staphylococcus epidermidis isolated from bloodstream and blood vessel catheter]." in: Kansenshōgaku zasshi. The Journal of the Japanese Association for Infectious Diseases, Vol. 74, Issue 2, pp. 96-103, (2000) (PubMed).

Antigendetails

Target: KSHVORF62

Substanzklasse: Viral Protein

Hintergrund:

Description: Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi's sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman's disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. At least five major proteins are likely to be involved in the assembly of the HHV-8 capsid, including a protease (encoded by ORF17), the major capsid protein (encoded by ORF25), and three other smaller capsid proteins (encoded by ORF62, ORF26, and ORF65). Previous structural studies have shown that the HSV-1 triplex is a monomer of VP19c and a dimer of VP23 and that the HCMV triplex is similarly composed of a monomer and a dimer. By analogy, the KSHV triplexes are likely also composed of a monomer of the ORF62 protein and a dimer of the ORF26 protein, which are the respective homologs of VP19c and VP23.

Aliases: ORF62

Gen-ID: 4961461

HGNC: 4961461