KRT15 Antikörper

Produktnummer ABIN969250

Produktdetails anti-KRT15 Antikörper

Target: KRT15 (Keratin 15 (KRT15))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser KRT15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of KRT15 expressed in E. coli.

Klon: 6-00E-07

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-KRT15 Antikörper (ABIN969250)

Radoja, Stojadinovic, Waseem, Tomic-Canic, Milisavljevic, Teebor, Blumenberg: "Thyroid hormones and gamma interferon specifically increase K15 keratin gene transcription." in: Molecular and cellular biology, Vol. 24, Issue 8, pp. 3168-79, (2004) (PubMed).

Werner, Munz: "Suppression of keratin 15 expression by transforming growth factor beta in vitro and by cutaneous injury in vivo." in: Experimental cell research, Vol. 254, Issue 1, pp. 80-90, (2000) (PubMed).

Details zu KRT15

Target: KRT15 (Keratin 15 (KRT15))

Andere Bezeichnung: KRT15 (KRT15 Produkte)

Synonyme: xlk2 antikoerper, CK15 antikoerper, K15 antikoerper, K1CO antikoerper, AI528832 antikoerper, Krt1-15 antikoerper, Ka15 antikoerper, wu:fa91c06 antikoerper, wu:fa95d04 antikoerper, zgc:55334 antikoerper, keratin 15, type I L homeolog antikoerper, keratin 15, type I antikoerper, keratin 15 antikoerper, krt15.L antikoerper, krt15 antikoerper, KRT15 antikoerper, Krt15 antikoerper

Hintergrund:

Description: The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 15 is a type I keratin without a defined type II partner. Keratin 15 is expressed primarily in the basal keratinocytes of stratified tissues, including the fetal epidermis and fetal nail. Expression of keratin 15 is downregulated in some hyperproliferating situations, such as psoriasis and hypertrophic scars. Because keratinocytes in psoriasis and hypertrophic scars are activated, it is suggested that keratin 15 expression is not compatible with keratinocyte activation and the keratin 15 gene is downregulated to maintain the activated phenotype.

Aliases: K15, CK15, K1CO, KRT1

Molekulargewicht: 49 kDa

Gen-ID: 3866

HGNC: 3866