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ITK Antikörper

ITK Reaktivität: Human WB, ELISA, ICC, FACS Wirt: Maus Monoclonal 5G6 unconjugated
Produktnummer ABIN969222
  • Target Alle ITK Antikörper anzeigen
    ITK (IL2-Inducible T-Cell Kinase (ITK))
    Reaktivität
    • 51
    • 20
    • 12
    • 6
    • 3
    Human
    Wirt
    • 63
    • 5
    • 2
    Maus
    Klonalität
    • 64
    • 6
    Monoklonal
    Konjugat
    • 31
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ITK Antikörper ist unkonjugiert
    Applikation
    • 43
    • 36
    • 14
    • 14
    • 12
    • 7
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human ITK expressed in E. coli.
    Klon
    5G6
    Isotyp
    IgG1
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Huck, Feyen, Niehues, Rüschendorf, Hübner, Laws, Telieps, Knapp, Wacker, Meindl, Jumaa, Borkhardt: "Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation." in: The Journal of clinical investigation, Vol. 119, Issue 5, pp. 1350-8, (2009) (PubMed).

    Kogina, Shoda, Yamaguchi, Tsuno, Takahashi, Fujio, Yamamoto: "Tacrolimus differentially regulates the proliferation of conventional and regulatory CD4(+) T cells." in: Molecules and cells, Vol. 28, Issue 2, pp. 125-30, (2009) (PubMed).

  • Target
    ITK (IL2-Inducible T-Cell Kinase (ITK))
    Andere Bezeichnung
    ITK (ITK Produkte)
    Synonyme
    Emt antikoerper, Tcsk antikoerper, Tsk antikoerper, EMT antikoerper, LPFS1 antikoerper, LYK antikoerper, PSCTK2 antikoerper, IL2 inducible T cell kinase antikoerper, IL2 inducible T-cell kinase antikoerper, IL2-inducible T-cell kinase antikoerper, Itk antikoerper, ITK antikoerper
    Hintergrund

    Description: This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation.

    Aliases: EMT, LYK, PSCTK2, MGC126257, MGC126258

    Molekulargewicht
    72 kDa
    Gen-ID
    3702
    HGNC
    3702
    Pathways
    T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung
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