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FGFR1 Antikörper (AA 22-376)

FGFR1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 3D4F7 unconjugated
Produktnummer ABIN969138
  • Target Alle FGFR1 Antikörper anzeigen
    FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))
    Bindungsspezifität
    • 33
    • 30
    • 20
    • 19
    • 19
    • 17
    • 16
    • 9
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 22-376
    Reaktivität
    • 246
    • 103
    • 101
    • 24
    • 22
    • 15
    • 8
    • 7
    • 4
    • 2
    • 2
    • 1
    Human
    Wirt
    • 239
    • 40
    • 1
    Maus
    Klonalität
    • 231
    • 49
    Monoklonal
    Konjugat
    • 124
    • 24
    • 21
    • 17
    • 13
    • 12
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    Dieser FGFR1 Antikörper ist unkonjugiert
    Applikation
    • 238
    • 120
    • 63
    • 63
    • 52
    • 36
    • 26
    • 24
    • 22
    • 17
    • 15
    • 9
    • 7
    • 5
    • 2
    • 1
    Western Blotting (WB), ELISA
    Aufreinigung
    purified
    Immunogen
    Purified recombinant extracellular fragment of human FGFR1 (aa22-376) fused with hIgGFc tag expressed in HEK293 cells.
    Klon
    3D4F7
    Isotyp
    IgG2b
    Top Product
    Discover our top product FGFR1 Primärantikörper
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Elbauomy Elsheikh, Green, Lambros, Turner, Grainge, Powe, Ellis, Reis-Filho: "FGFR1 amplification in breast carcinomas: a chromogenic in situ hybridisation analysis." in: Breast cancer research : BCR, Vol. 9, Issue 2, pp. R23, (2007) (PubMed).

    Magnusson, Ronca, DellEra, Carlstedt, Jakobsson, Partanen, Dimberg, Claesson-Welsh: "Fibroblast growth factor receptor-1 expression is required for hematopoietic but not endothelial cell development." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 25, Issue 5, pp. 944-9, (2005) (PubMed).

    Hu, Fang, Dunham, Prada, Stachowiak, Stachowiak: "90-kDa ribosomal S6 kinase is a direct target for the nuclear fibroblast growth factor receptor 1 (FGFR1): role in FGFR1 signaling." in: The Journal of biological chemistry, Vol. 279, Issue 28, pp. 29325-35, (2004) (PubMed).

  • Target
    FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))
    Andere Bezeichnung
    FGFR1 (FGFR1 Produkte)
    Synonyme
    FGFR antikoerper, fgfr antikoerper, X1FGFR antikoerper, XFGFR-1 antikoerper, XFGFRA2 antikoerper, bfgfr antikoerper, cek antikoerper, fgfr1 antikoerper, flg antikoerper, flt-2 antikoerper, flt2 antikoerper, kal2 antikoerper, ogd antikoerper, xfgfr1 antikoerper, CG7223 antikoerper, CT22273 antikoerper, CT39172 antikoerper, DFGF-R1 antikoerper, DFGF-R2 antikoerper, DFR-1 antikoerper, DFR1 antikoerper, DFR1/DFGF-R2 antikoerper, DPR3 antikoerper, DTRK(FR1) antikoerper, Dfr-1 antikoerper, Dfr1 antikoerper, DmHD-38 antikoerper, Dmel\\CG7223 antikoerper, Dtk1 antikoerper, EMS2 antikoerper, FGF-R2 antikoerper, FGFR2 antikoerper, FR1 antikoerper, Fr1 antikoerper, HD-38 antikoerper, HTL/FGFR1 antikoerper, Htl antikoerper, Tk1 antikoerper, dtk1 antikoerper, i100 antikoerper, i150 antikoerper, i79 antikoerper, j372 antikoerper, cd331 antikoerper, fgfbr antikoerper, fgfr-1 antikoerper, hbgfr antikoerper, n-sam antikoerper, ach antikoerper, cd333 antikoerper, cek2 antikoerper, fgfr-3 antikoerper, hsfgfr3ex antikoerper, jtk4 antikoerper, BFGFR antikoerper, CD331 antikoerper, CEK antikoerper, FGFBR antikoerper, FGFR-1 antikoerper, FLG antikoerper, FLT-2 antikoerper, FLT2 antikoerper, HBGFR antikoerper, HH2 antikoerper, KAL2 antikoerper, N-SAM antikoerper, OGD antikoerper, bFGF-R-1 antikoerper, AW208770 antikoerper, Eask antikoerper, Fgfr-1 antikoerper, Flt-2 antikoerper, Hspy antikoerper, FLG-1 antikoerper, FGFRI antikoerper, x1fgfr antikoerper, cb231 antikoerper, sb:cb231 antikoerper, fibroblast growth factor receptor antikoerper, fibroblast growth factor receptor 1 S homeolog antikoerper, basic fibroblast growth factor receptor 1 antikoerper, heartless antikoerper, fibroblast growth factor receptor 1 antikoerper, fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) L homeolog antikoerper, Fibroblast growth factor receptor 1 antikoerper, fibroblast growth factor receptor 1 L homeolog antikoerper, fibroblast growth factor receptor 1a antikoerper, FGFR antikoerper, fgfr antikoerper, fgfr1.S antikoerper, CpipJ_CPIJ005849 antikoerper, htl antikoerper, fgfr1 antikoerper, fgfr3.L antikoerper, FGFR1 antikoerper, Fgfr1 antikoerper, fgfr1.L antikoerper, fgfr1a antikoerper
    Hintergrund

    Description: Fibroblast growth factor receptor 1 (FGFR1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome, and CD331, is a receptor tyrosine kinase whose ligands are specific members of the fibroblast growth factor family. FGFR1 has been shown to be associated with Pfeiffer syndrome. It is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction.

    Aliases: CEK, FLG, OGD, FLT2, KAL2, BFGFR, CD331, FGFBR, HBGFR

    Molekulargewicht
    92 kDa
    Gen-ID
    2260
    HGNC
    2260
    Pathways
    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Sensory Perception of Sound, Stem Cell Maintenance, S100 Proteine
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