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Fibulin 5 Antikörper (AA 242-448)

FBLN5 Reaktivität: Human WB, ELISA, IHC Wirt: Maus Monoclonal 1G6A4 unconjugated
Produktnummer ABIN969131
  • Target Alle Fibulin 5 (FBLN5) Antikörper anzeigen
    Fibulin 5 (FBLN5)
    Bindungsspezifität
    • 12
    • 8
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 242-448
    Reaktivität
    • 52
    • 30
    • 23
    • 1
    Human
    Wirt
    • 52
    • 5
    • 1
    Maus
    Klonalität
    • 53
    • 7
    Monoklonal
    Konjugat
    • 27
    • 8
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Fibulin 5 Antikörper ist unkonjugiert
    Applikation
    • 55
    • 31
    • 14
    • 5
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of FBLN5 (aa242-448) expressed in E. coli.
    Klon
    1G6A4
    Isotyp
    IgG1
    Top Product
    Discover our top product FBLN5 Primärantikörper
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Wang, LeMaire, Chen, Carter, Shen, Gan, Bartsch, Wilks, Utama, Ou, Thompson, Coselli, Wang: "Decreased expression of fibulin-5 correlates with reduced elastin in thoracic aortic dissection." in: Surgery, Vol. 138, Issue 2, pp. 352-9, (2005) (PubMed).

    Stone, Braun, Russell, Kuehn, Lotery, Moore, Eastman, Casavant, Sheffield: "Missense variations in the fibulin 5 gene and age-related macular degeneration." in: The New England journal of medicine, Vol. 351, Issue 4, pp. 346-53, (2004) (PubMed).

    Markova, Zou, Ringpfeil, Sasaki, Kostka, Timpl, Uitto, Chu: "Genetic heterogeneity of cutis laxa: a heterozygous tandem duplication within the fibulin-5 (FBLN5) gene." in: American journal of human genetics, Vol. 72, Issue 4, pp. 998-1004, (2003) (PubMed).

  • Target
    Fibulin 5 (FBLN5)
    Andere Bezeichnung
    FBLN5 (FBLN5 Produkte)
    Synonyme
    zgc:103575 antikoerper, FBLN5 antikoerper, MGC108414 antikoerper, Fibulin-5 antikoerper, DKFZp469K0327 antikoerper, ADCL2 antikoerper, ARCL1A antikoerper, ARMD3 antikoerper, DANCE antikoerper, EVEC antikoerper, FIBL-5 antikoerper, UP50 antikoerper, A55 antikoerper, fibulin 5 antikoerper, fbln5 antikoerper, FBLN5 antikoerper, Fbln5 antikoerper
    Hintergrund

    Description: FBLN5: fibulin 5. The protein is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling.

    Aliases: EVEC, UP50, ARMD3, DANCE

    Gen-ID
    10516
    HGNC
    10516
    Pathways
    SARS-CoV-2 Protein Interaktom
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