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p300 Antikörper

EP300 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 7D8A6 unconjugated
Produktnummer ABIN969098
  • Target Alle p300 (EP300) Antikörper anzeigen
    p300 (EP300) (E1A Binding Protein P300 (EP300))
    Reaktivität
    • 86
    • 43
    • 27
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 77
    • 13
    Maus
    Klonalität
    • 78
    • 12
    Monoklonal
    Konjugat
    • 51
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser p300 Antikörper ist unkonjugiert
    Applikation
    • 64
    • 41
    • 36
    • 20
    • 16
    • 15
    • 15
    • 15
    • 12
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of EP300 expressed in E. coli.
    Klon
    7D8A6
    Isotyp
    IgG1
    Top Product
    Discover our top product EP300 Primärantikörper
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Geiger, Sharma, Kim, Nyborg: "The human T-cell leukemia virus type 1 tax protein confers CBP/p300 recruitment and transcriptional activation properties to phosphorylated CREB." in: Molecular and cellular biology, Vol. 28, Issue 4, pp. 1383-92, (2008) (PubMed).

    Stauffer, Chang, Huang, Dunn, Thayer: "p300/CREB-binding protein interacts with ATR and is required for the DNA replication checkpoint." in: The Journal of biological chemistry, Vol. 282, Issue 13, pp. 9678-87, (2007) (PubMed).

  • Target
    p300 (EP300) (E1A Binding Protein P300 (EP300))
    Andere Bezeichnung
    EP300 (EP300 Produkte)
    Synonyme
    KAT3B antikoerper, RSTS2 antikoerper, p300 antikoerper, A430090G16 antikoerper, A730011L11 antikoerper, p300 HAT antikoerper, E1A binding protein p300 antikoerper, histone acetyltransferase p300 antikoerper, EP300 antikoerper, LOC446056 antikoerper, ep300 antikoerper, Ep300 antikoerper
    Hintergrund

    Description: EP300: E1A binding protein p300. This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.

    Aliases: p300, KAT3B

    Gen-ID
    2033
    HGNC
    2033
    Pathways
    p53 Signalweg, Notch Signalweg, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Regulation of Cell Size
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