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CDK1 Antikörper

CDK1 Reaktivität: Human WB, ELISA, FACS, ICC Wirt: Maus Monoclonal 8C5A7F10 unconjugated
Produktnummer ABIN969034
  • Target Alle CDK1 Antikörper anzeigen
    CDK1 (Cyclin-Dependent Kinase 1 (CDK1))
    Reaktivität
    • 321
    • 180
    • 116
    • 39
    • 35
    • 31
    • 25
    • 20
    • 15
    • 14
    • 12
    • 11
    • 11
    • 9
    • 7
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 268
    • 63
    Maus
    Klonalität
    • 255
    • 76
    Monoklonal
    Konjugat
    • 166
    • 27
    • 17
    • 15
    • 11
    • 10
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser CDK1 Antikörper ist unkonjugiert
    Applikation
    • 263
    • 123
    • 67
    • 61
    • 54
    • 53
    • 53
    • 49
    • 47
    • 20
    • 20
    • 16
    • 6
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of CDC2 expressed in E. coli.
    Klon
    8C5A7F10
    Isotyp
    IgG1
    Top Product
    Discover our top product CDK1 Primärantikörper
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Meyer, Merkel, Brückl, Schellerer, Schildberg, Campean, Hohenberger, Croner: "Cdc2 as prognostic marker in stage UICC II colon carcinomas." in: European journal of cancer (Oxford, England : 1990), Vol. 45, Issue 8, pp. 1466-73, (2009) (PubMed).

    Tang, Wu, Guo, Hansen, Perry, Freel, Nutt, Jackson, Kornbluth: "Cdc2 and Mos regulate Emi2 stability to promote the meiosis I-meiosis II transition." in: Molecular biology of the cell, Vol. 19, Issue 8, pp. 3536-43, (2008) (PubMed).

  • Target
    CDK1 (Cyclin-Dependent Kinase 1 (CDK1))
    Andere Bezeichnung
    CDC2 (CDK1 Produkte)
    Synonyme
    CDC2 antikoerper, CDC28A antikoerper, P34CDC2 antikoerper, Cdc2 antikoerper, Cdc2a antikoerper, p34 antikoerper, cdc2 antikoerper, wu:fc30e01 antikoerper, zgc:92032 antikoerper, PSTAIR antikoerper, cdc-2 antikoerper, cdc2-a antikoerper, cdc28a antikoerper, cdc2x1.1 antikoerper, p34cdc2 antikoerper, xcdc2 antikoerper, 5363 antikoerper, CDCDm antikoerper, CDK1 antikoerper, CDK1/CDC2 antikoerper, CG5363 antikoerper, Cdk-1 antikoerper, Cdk1 antikoerper, Dcdc2 antikoerper, Dm cdc2 antikoerper, DmCdc2 antikoerper, DmCdk1 antikoerper, Dmcdc2 antikoerper, Dmel\\CG5363 antikoerper, cdc antikoerper, cdc2Dm antikoerper, cdk1 antikoerper, dCdk1 antikoerper, group 4 antikoerper, l(2)31Eh antikoerper, CDC2A antikoerper, CDC2AAT antikoerper, CDK2 antikoerper, CDKA1 antikoerper, CDKA;1 antikoerper, CYCLIN-DEPENDENT KINASE A;1 antikoerper, cell division control 2 antikoerper, cdc2-b antikoerper, cdc2a antikoerper, cdc2x1.2 antikoerper, POL3 antikoerper, pold antikoerper, cyclin dependent kinase 1 antikoerper, cyclin dependent kinase like 1 antikoerper, Cell division control protein 2 1 antikoerper, cyclin-dependent kinase 1 antikoerper, cyclin-dependent kinase 1 S homeolog antikoerper, Cyclin-dependent kinase 1 antikoerper, cell division control 2 antikoerper, cell division control protein2 homolog antikoerper, cyclin-dependent kinase 1 L homeolog antikoerper, polymerase (DNA directed), delta 1, catalytic subunit L homeolog antikoerper, cyclin-dependent protein kinase Cdk1/Cdc2 antikoerper, CDK1 antikoerper, CDKL1 antikoerper, POPTR_0004s14080g antikoerper, Cdk1 antikoerper, cdk1 antikoerper, cdk1.S antikoerper, CDC2 antikoerper, cdc2 antikoerper, cdk-1 antikoerper, cdk1.L antikoerper, pold1.L antikoerper
    Hintergrund

    Description: The cell division control protein cdc2, also known as cyclin-dependent kinase 1 (Cdk1) or p34/cdk1, plays a key role in the control of the eukaryotic cell cycle, where it is required for entry into S-phase and mitosis. Cdc2 exists as a complex with both cyclin A and cyclin B. The best characterized of these associations is the Cdc2 p34 cyclin B complex, which is required for the G2 to M phase transition. Activation of Cdc2 is controlled at several steps including cyclin binding and phosphorylation of threonine 161. However, the critical regulatory step in activating cdc2 during progression into mitosis appears to be dephosphorylation of Tyr15 and Tyr14. Phosphorylation at Tyr15 and inhibition of Cdc2 is carried out by WEE1 and MIK protein kinases while Tyr15 dephosphorylation and activation of Cdc2 is carried out by the cdc25 phosphatase. The isoform CDC2deltaT is found in breast cancer tissues. Furthermore, cdc2/Cdk1 is a key mediator of neuronal cell death in brain development and degeneration.

    Aliases: CDC2, CDC28A, P34CDC2, MGC111195, DKFZp686L20222, CDK1

    Molekulargewicht
    34 kDa
    Gen-ID
    983
    HGNC
    983
    Pathways
    Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA
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