APOB Antikörper
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- Target Alle APOB Antikörper anzeigen
- APOB (Apolipoprotein B (APOB))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser APOB Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human ApoB expressed in E. coli.
- Klon
- 6G6
- Isotyp
- IgG1
- Top Product
- Discover our top product APOB Primärantikörper
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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Apolipoprotein B levels, APOB alleles, and risk of ischemic cardiovascular disease in the general population, a review." in: Atherosclerosis, Vol. 206, Issue 1, pp. 17-30, (2009) (PubMed).
: "Apolipoprotein B Is an innate barrier against invasive Staphylococcus aureus infection." in: Cell host & microbe, Vol. 4, Issue 6, pp. 555-66, (2008) (PubMed).
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Apolipoprotein B levels, APOB alleles, and risk of ischemic cardiovascular disease in the general population, a review." in: Atherosclerosis, Vol. 206, Issue 1, pp. 17-30, (2009) (PubMed).
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- Target
- APOB (Apolipoprotein B (APOB))
- Andere Bezeichnung
- ApoB (APOB Produkte)
- Synonyme
- FLDB antikoerper, LDLCQ4 antikoerper, Ac1-060 antikoerper, Apo B-100 antikoerper, ApoB-100 antikoerper, ApoB-48 antikoerper, AI315052 antikoerper, apob-100 antikoerper, apob-48 antikoerper, APOB-100 antikoerper, ApoB(100) antikoerper, APOB antikoerper, apolipoprotein B antikoerper, APOB antikoerper, Apob antikoerper
- Hintergrund
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Description: This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.
Aliases: FLDB, LDLCQ4
- Molekulargewicht
- 516 kDa
- Gen-ID
- 338
- HGNC
- 338
- Pathways
- Lipid Metabolism
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