Apoa5(bd) (AA 180-363) Antikörper

Produktnummer ABIN968960

Produktdetails

Target: Apoa5(bd)

Bindungsspezifität: AA 180-363

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: ELISA

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human APOA5 (AA: 180-363) expressed in E. coli.

Klon: 4H8H8E2(c)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Antigendetails

Target: Apoa5(bd)

Andere Bezeichnung: Apoa5 (bd)

Hintergrund:

Description: Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglyc erides, whereas a knock-in model with human ApoA5 produced 50-70 % lower , , concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor-_ agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Recently, it was demonstrated that ApoA5 is present in human serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentration than other apolipoproteins.

Aliases: RAP3, APOAV, APOA-V

Molekulargewicht: 41.2 kDa

Gen-ID: 116519

HGNC: 116519