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EZH2 Antikörper (AA 156-256)

EZH2 Reaktivität: Human, Maus, Ratte, Hund, Huhn WB, IF Wirt: Maus Monoclonal 11-EZH2 unconjugated
Produktnummer ABIN968906
  • Target Alle EZH2 Antikörper anzeigen
    EZH2 (Enhancer of Zeste Homolog 2 (EZH2))
    Bindungsspezifität
    • 16
    • 15
    • 15
    • 7
    • 7
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 156-256
    Reaktivität
    • 133
    • 66
    • 33
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Hund, Huhn
    Wirt
    • 107
    • 27
    • 1
    Maus
    Klonalität
    • 99
    • 36
    Monoklonal
    Konjugat
    • 66
    • 10
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EZH2 Antikörper ist unkonjugiert
    Applikation
    • 74
    • 40
    • 36
    • 27
    • 23
    • 18
    • 14
    • 13
    • 12
    • 10
    • 8
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (IF)
    Kreuzreaktivität
    Hund, Ratte (Rattus), Maus, Huhn
    Produktmerkmale
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    Aufreinigung
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogen
    Human EZH2 recombinant protein aa. 156-256
    Klon
    11-EZH2
    Isotyp
    IgG1
    Top Product
    Discover our top product EZH2 Primärantikörper
  • Kommentare

    Related Products: ABIN968537, ABIN967389

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    250 μg/mL
    Buffer
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store undiluted at -20°C.
  • Raaphorst, Otte, van Kemenade, Blokzijl, Fieret, Hamer, Satijn, Meijer: "Distinct BMI-1 and EZH2 expression patterns in thymocytes and mature T cells suggest a role for Polycomb genes in human T cell differentiation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 10, pp. 5925-34, (2001) (PubMed).

    van Kemenade, Raaphorst, Blokzijl, Fieret, Hamer, Satijn, Otte, Meijer: "Coexpression of BMI-1 and EZH2 polycomb-group proteins is associated with cycling cells and degree of malignancy in B-cell non-Hodgkin lymphoma." in: Blood, Vol. 97, Issue 12, pp. 3896-901, (2001) (PubMed).

  • Target
    EZH2 (Enhancer of Zeste Homolog 2 (EZH2))
    Andere Bezeichnung
    EZH2 (EZH2 Produkte)
    Synonyme
    ENX-1 antikoerper, ENX1 antikoerper, EZH1 antikoerper, EZH2b antikoerper, KMT6 antikoerper, KMT6A antikoerper, WVS antikoerper, WVS2 antikoerper, eya2 antikoerper, im:7149338 antikoerper, zgc:136376 antikoerper, zgc:152758 antikoerper, EZH2 antikoerper, enx-1 antikoerper, enx1 antikoerper, ezh1 antikoerper, kmt6 antikoerper, xez antikoerper, Enx-1 antikoerper, Enx1h antikoerper, mKIAA4065 antikoerper, ezh2 antikoerper, olezh2 antikoerper, enhancer of zeste 2 polycomb repressive complex 2 subunit antikoerper, enhancer of zeste 2 polycomb repressive complex 2 subunit L homeolog antikoerper, enhancer of zeste 2 polycomb repressive complex 2 subunit S homeolog antikoerper, EZH2 antikoerper, ezh2 antikoerper, Ezh2 antikoerper, ezh2.L antikoerper, ezh2.S antikoerper
    Hintergrund
    The Polycomb group (PcG) of gene products are essential for the maintenance, but not initiation, of the transcriptionally repressed state of development genes. Those genes encode a structurally diverse group of proteins with conserved functions from flies to human cells and from complexes as a result of mutual associations ultimately influencing gene expression. EZH2 is a human homologue of Drosophil's Enhancer of Zeste gene, an important regulator of homeobox gene expression. The expression of EZH2 was seen in follicular T cells and at different stages during T-cell differentiation. Additionally, in lymphocytes, EZH2 interacts with the signal transduction protein Vav and is highly expressed in a variety of tumors such as lymphoma and prostate. The predicted molecular weight for this protein is approximately 85 kDa (SwissProt:Q15910).
    Molekulargewicht
    91 kDa
    Pathways
    Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation
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