Neural Cell Adhesion Molecule 1 (NCAM1) Antikörper

Antigen: Neural Cell Adhesion Molecule 1 (NCAM1)

Synonyme: CD56, NCAM, MSK39, ncam, fj56g09, wu:fj56g09, NCAM1, n-cam, LOC397761

Klonalität: Monoklonal (1213C3-D5)

Wirt: Maus

Reaktivität: Human

Applikation: Immunhistochemie (Paraffinschnitte) (IHC (p))

Produktnummer: ABIN96870

Produktbeschreibung

Weitere Bezeichnung: CD56

Immunogen: BALB/C mice were injected with membrane preparation of a small cell lung carcinoma.

Format: Supernatant

Isotyp: IgG1 kappa  (Passende Sekundärantikörper)

Klon: 1213C3-D5

Spezifität: This antibody is specific to two proteins of 185 kD and 145 kD, identified as two isoforms of neural cell adhesion molecules (NCAM/CD56). NCAM is expressed on most neuroectodermal derived cell lines, tissues and neoplasm such as retinoblastoma, medulloblastoma, astrocytomas and neuroblastoma.

Anwendungen

Applikationshinweise: Titer/Working Dilution: This antibody may be diluted to a titer of 1:25-1:75 in an ABC method. However, depending on the staining conditions employed, we suggest that final dilution should be determined by the user. Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10mM citrate buffer, pH 6.0 prior to immunostaining. Positive Control: Neuroblastoma. Cellular localization: Cell membrane

Konzentration: 100ug/ml approximately

Buffer: This antibody is supplied as purified immunoglobulin fraction containing sodium azide as preservative.

Lagerung: Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.

Forschungsgebiet: CD Antigene

Beschränkungen: Für Forschungszwecke. Als CE-zertifizierter Antikörper in der Europäischen Union für In Vitro Diagnostik (IVD) zugelassen.

Bilder

Formalin fixed paraffin embedded human tonsil stained with CD56, NCAM-1 antibody

Publikationen

Publikationen: Kibbelaar, Moolenaar, Michalides et al.: "Neural cell adhesion molecule expression, neuroendocrine differentiation and prognosis in lung carcinoma." in: European journal of cancer (Oxford, England : 1990), Vol. 27, Issue 4, pp. 431-5, 1991 (PubMed).

Michalides, Kwa, Springall et al.: "NCAM and lung cancer." in: International journal of cancer. Supplement = Journal international du cancer. Supplement, Vol. 8, pp. 34-7, 1994 (PubMed).