DYNLL1 Antikörper (AA 1-89)
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- Target Alle DYNLL1 Antikörper anzeigen
- DYNLL1 (Dynein, Light Chain, LC8-Type 1 (DYNLL1))
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Bindungsspezifität
- AA 1-89
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Reaktivität
- Human, Ratte
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser DYNLL1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Kreuzreaktivität
- Human
- Produktmerkmale
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - Aufreinigung
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- Immunogen
- Rat PIN aa. 1-89
- Klon
- 4-PIN
- Isotyp
- IgG1
- Top Product
- Discover our top product DYNLL1 Primärantikörper
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- Kommentare
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Related Products: ABIN968545, ABIN967389
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 250 μg/mL
- Buffer
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store undiluted at -20° C.
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Cytoplasmic dynein (ddlc1) mutations cause morphogenetic defects and apoptotic cell death in Drosophila melanogaster." in: Molecular and cellular biology, Vol. 16, Issue 5, pp. 1966-77, (1996) (PubMed).
: "PIN: an associated protein inhibitor of neuronal nitric oxide synthase." in: Science (New York, N.Y.), Vol. 274, Issue 5288, pp. 774-7, (1996) (PubMed).
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Cytoplasmic dynein (ddlc1) mutations cause morphogenetic defects and apoptotic cell death in Drosophila melanogaster." in: Molecular and cellular biology, Vol. 16, Issue 5, pp. 1966-77, (1996) (PubMed).
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- Target
- DYNLL1 (Dynein, Light Chain, LC8-Type 1 (DYNLL1))
- Andere Bezeichnung
- PIN (DYNLL1 Produkte)
- Synonyme
- DLC1 antikoerper, DLC8 antikoerper, DNCL1 antikoerper, DNCLC1 antikoerper, LC8 antikoerper, LC8a antikoerper, PIN antikoerper, hdlc1 antikoerper, dynll2 antikoerper, wu:fd56c09 antikoerper, zgc:73406 antikoerper, Dlc8 antikoerper, Dnclc1 antikoerper, Pin antikoerper, 8kDLC antikoerper, lc8 antikoerper, dlc1 antikoerper, dlc8 antikoerper, lc8a antikoerper, dncl1 antikoerper, dnclc1 antikoerper, dynll1a antikoerper, MGC68763 antikoerper, CDLC2 antikoerper, dynll1 antikoerper, dynll1b antikoerper, pin antikoerper, MGC89636 antikoerper, dynein light chain LC8-type 1 antikoerper, dynein, light chain, LC8-type 1 antikoerper, dynein light chain LC8-type 1 S homeolog antikoerper, dynein light chain LC8-type 1 L homeolog antikoerper, Dynein light chain 1, cytoplasmic antikoerper, DYNLL1 antikoerper, dynll1 antikoerper, Dynll1 antikoerper, dynll1.S antikoerper, dynll1.L antikoerper, dlc-1 antikoerper
- Hintergrund
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PIN (protein inhibitor of nNOS) is a small protein of 89 amino acids initially described as a light chain subunit of dynein and as an inhibitor of the neuronal nitric oxide synthase isoform (nNOS). In vitro, PIN has been reported to bind to a unique nNOS domain encompassing amino acids 163-245. PIN inhibits nNOS activity and blocks the formation of the active nNOS dimer. Although ubiquitously expressed, PIN levels are reportedly highest in brain and testis. Immunolocalization studies in Drosophila melanogaster detected a cytoplasmic distribution of PIN. Partial-loss-of-function of PIN resulted in morphologic and developmental changes in the bristles, wings, and female sterility of D. melanogaster. Deletion of PIN resulted in lethality with the characteristic morphology of apoptotic cells. This antibody is routinely tested by western blot analysis.
Synonyms: Protein Inhibitor of nNOS - Molekulargewicht
- 10 kDa
- Pathways
- M Phase, Tube Formation, Positive Regulation of Endopeptidase Activity
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