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Liver Arginase Antikörper (AA 53-207)

ARG1 Reaktivität: Ratte, Maus, Blow Fly WB, IHC, IF, IP Wirt: Maus Monoclonal 19-Arginase I unconjugated
Produktnummer ABIN968128
  • Target Alle Liver Arginase (ARG1) Antikörper anzeigen
    Liver Arginase (ARG1) (Arginase, Liver (ARG1))
    Bindungsspezifität
    • 24
    • 20
    • 16
    • 12
    • 12
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 53-207
    Reaktivität
    • 112
    • 63
    • 41
    • 9
    • 8
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Ratte, Maus, Blow Fly
    Wirt
    • 111
    • 29
    • 5
    • 3
    • 2
    Maus
    Klonalität
    • 108
    • 42
    Monoklonal
    Konjugat
    • 85
    • 13
    • 11
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Liver Arginase Antikörper ist unkonjugiert
    Applikation
    • 102
    • 59
    • 36
    • 30
    • 22
    • 21
    • 15
    • 14
    • 13
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    Kreuzreaktivität
    Maus, Ratte (Rattus), Fruchtfliege (Drosophila melanogaster)
    Produktmerkmale
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    Aufreinigung
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogen
    Human Arginase I aa. 53-207
    Klon
    19-Arginase I
    Isotyp
    IgG1
    Top Product
    Discover our top product ARG1 Primärantikörper
  • Kommentare

    Related Products: ABIN968543, ABIN967389

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    250 μg/mL
    Buffer
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store undiluted at -20° C.
  • Morrison, Correll: "Activation of the stem cell-derived tyrosine kinase/RON receptor tyrosine kinase by macrophage-stimulating protein results in the induction of arginase activity in murine peritoneal macrophages." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 2, pp. 853-60, (2002) (PubMed).

    Chang, Zoghi, Liao, Kuo: "The involvement of tyrosine kinases, cyclic AMP/protein kinase A, and p38 mitogen-activated protein kinase in IL-13-mediated arginase I induction in macrophages: its implications in IL-13-inhibited nitric oxide production." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 4, pp. 2134-41, (2000) (PubMed).

    Sonoki, Nagasaki, Gotoh, Takiguchi, Takeya, Matsuzaki, Mori: "Coinduction of nitric-oxide synthase and arginase I in cultured rat peritoneal macrophages and rat tissues in vivo by lipopolysaccharide." in: The Journal of biological chemistry, Vol. 272, Issue 6, pp. 3689-93, (1997) (PubMed).

    Dizikes, Grody, Kern, Cederbaum: "Isolation of human liver arginase cDNA and demonstration of nonhomology between the two human arginase genes." in: Biochemical and biophysical research communications, Vol. 141, Issue 1, pp. 53-9, (1987) (PubMed).

    Haraguchi, Takiguchi, Amaya, Kawamoto, Matsuda, Mori: "Molecular cloning and nucleotide sequence of cDNA for human liver arginase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 84, Issue 2, pp. 412-5, (1987) (PubMed).

  • Target
    Liver Arginase (ARG1) (Arginase, Liver (ARG1))
    Andere Bezeichnung
    Arginase I (ARG1 Produkte)
    Synonyme
    SI:zC146F4.4 (novel protein with NUDIX domain) antikoerper, si:ch211-146f4.3 antikoerper, argi1 antikoerper, AI antikoerper, AI256583 antikoerper, Arg-1 antikoerper, PGIF antikoerper, arginase 1 antikoerper, arginase antikoerper, Arginase-1 antikoerper, arginase, liver antikoerper, L-arginase antikoerper, arg1 antikoerper, PGTG_16455 antikoerper, argi1 antikoerper, ARG1 antikoerper, Arg1 antikoerper
    Hintergrund
    Arginase converts arginine into urea plus ornithine, the final step in urea synthesis. Two different isoforms (I&II) have been isolated with approximately 60% homology at the nucleotide level. While type II is present in many tissues, Arginase I is expressed exclusively in liver. In cultured macrophages, as well as in vivo, Arginase I is induced with nitric oxide synthase (NOS) and the arginase I transactivator C/EBPbeta in response to lipopolysaccharide. This response occurs in a dose and time-dependent manner. While the mRNA for NOS appears as early as 2h after treatment, mRNA levels for arginase I peak after twelve hours of lipopolysaccharide treatment. Since the synthesis of nitric oxide by NOS requires arginine, the delayed induction of arginase I may be necessary for the regulation of NOS activity. This antibody is routinely tested by western blot analysis.
    Molekulargewicht
    35 kDa
    Pathways
    Cellular Response to Molecule of Bacterial Origin
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