5'-Nucleotidase, Cytosolic III (NT5C3) (AA 54-221) Antikörper

Details zu Produkt Nr. ABIN968020, Anbieter: Anmelden zum Anzeigen
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  • NT5C3
  • nt5c3
  • PYN1
  • 1600024P05Rik
  • 2610206B05Rik
  • 3110004A18Rik
  • AI842776
  • Nt5c3a
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  • PN-1
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  • PSN1
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  • p36
  • P5'N-1
  • P5N-1
  • POMP
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  • 5'-nucleotidase, cytosolic IIIA
  • 5'-nucleotidase, cytosolic III
  • cytosolic 5'-nucleotidase 3A
  • polyhomeotic-like 2 (Drosophila)
  • NT5C3A
  • Bm1_56095
  • nt5c3a
  • LOC534181
  • Nt5c3
  • nt5c3a.L
  • Nt5c3a
  • Phc2
Epitop
AA 54-221
3
2
2
1
1
1
1
1
1
1
Reaktivität
Maus
18
11
4
2
2
2
1
1
1
1
1
1
Wirt
Maus
22
1
Klonalität (Klon)
Monoklonal ()
Konjugat
Unkonjugiert
1
Applikation
Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
22
16
10
4
3
3
2
2
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen Mouse p36
Klon 6
Isotyp IgG1
Kreuzreaktivität Human, Ratte (Rattus), Hund, Huhn, Frosch
Produktmerkmale 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
Reinigung Purified from tissue culture supernatant or ascites by affinity chromatography.
Andere Bezeichnung p36 (NT5C3 Antibody Abstract)
Hintergrund Regulation of the cell cycle by cyclin-dependent kinases (cdks) is controlled by the phosphorylation of a conserved threonine residue in their catalytic subunit. Cdks are activated as a result of the phosphorylation of another cyclin-dependent kinase, cdk-activating kinase (CAK). This kinase has two subunits: the catalytic Cdk7 and the regulatory cyclin H. A 36 kDa protein, p36 (also known as Menage A Trois-1 (MAT1)), coimmunoprecipitates with CAK. p36 is a member of the RING finger family of proteins characterized by a C3HC4 zinc-binding domain. p36 functions as a CAK assembly factor and is involved in the regulation of CAK activation.
Synonyms: MAT1, Menage A Trois-1
Molekulargewicht 36 kDa
Kommentare

Related Products: ABIN968555, ABIN967389

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 250 µg/ml
Buffer Aqueous buffered solution containing BSA, glycerol.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Bilder des Herstellers
Western Blotting (WB) image for anti-5'-Nucleotidase, Cytosolic III (NT5C3) (AA 54-221) antibody (ABIN968020) Western blot analysis of p36 on a mouse macrophage cell lysate. Lane 1: 1:1000, lane ...
Immunofluorescence (IF) image for anti-5'-Nucleotidase, Cytosolic III (NT5C3) (AA 54-221) antibody (ABIN968020) Immunofluorescence staining of rat fibroblasts.
 image for anti-5'-Nucleotidase, Cytosolic III (NT5C3) (AA 54-221) antibody (ABIN968020) anti-5'-Nucleotidase, Cytosolic III (NT5C3) (AA 54-221) antibody (Image 3)
Produkt verwendet in: Saitoh, Pizzi, Wang: "Perturbation of SUMOlation enzyme Ubc9 by distinct domain within nucleoporin RanBP2/Nup358." in: The Journal of biological chemistry, Vol. 277, Issue 7, pp. 4755-63, 2002 (PubMed).

Takasaki, Kogure, Takeuchi, Kaneda, Yano, Hirokawa, Hirose, Shirai, Hashimoto: "Reactivity of anti-proliferating cell nuclear antigen (PCNA) murine monoclonal antibodies and human autoantibodies to the PCNA multiprotein complexes involved in cell proliferation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 7, pp. 4780-7, 2001 (PubMed).

Fisher, Jin, Chamberlin, Morgan: "Alternative mechanisms of CAK assembly require an assembly factor or an activating kinase." in: Cell, Vol. 83, Issue 1, pp. 47-57, 1995 (PubMed).

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