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NUP62 Antikörper (AA 24-178)

NUP62 Reaktivität: Human, Maus, Ratte, Huhn WB, IHC, IF, IP Wirt: Maus Monoclonal 53-Nucleoporin p62 unconjugated
Produktnummer ABIN968004
  • Target Alle NUP62 Antikörper anzeigen
    NUP62 (Nucleoporin 62kDa (NUP62))
    Bindungsspezifität
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 24-178
    Reaktivität
    • 45
    • 15
    • 15
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Huhn
    Wirt
    • 36
    • 7
    • 1
    • 1
    Maus
    Klonalität
    • 37
    • 8
    Monoklonal
    Konjugat
    • 35
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NUP62 Antikörper ist unkonjugiert
    Applikation
    • 35
    • 12
    • 10
    • 10
    • 9
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    Kreuzreaktivität
    Huhn, Maus, Ratte (Rattus)
    Produktmerkmale
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    Aufreinigung
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogen
    Human Nucleoporin aa. 24-178
    Klon
    53-Nucleoporin p62
    Isotyp
    IgG2b
    Top Product
    Discover our top product NUP62 Primärantikörper
  • Kommentare

    Related Products: ABIN968535, ABIN967389

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    250 μg/mL
    Buffer
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store undiluted at -20° C.
  • Paroni, Henderson, Schneider, Brancolini: "Caspase-2 can trigger cytochrome C release and apoptosis from the nucleus." in: The Journal of biological chemistry, Vol. 277, Issue 17, pp. 15147-61, (2002) (PubMed).

    Shah, Patel, Fried, Sehgal: "Interactions of STAT3 with caveolin-1 and heat shock protein 90 in plasma membrane raft and cytosolic complexes. Preservation of cytokine signaling during fever." in: The Journal of biological chemistry, Vol. 277, Issue 47, pp. 45662-9, (2002) (PubMed).

    Daigle, Beaudouin, Hartnell, Imreh, Hallberg, Lippincott-Schwartz, Ellenberg: "Nuclear pore complexes form immobile networks and have a very low turnover in live mammalian cells." in: The Journal of cell biology, Vol. 154, Issue 1, pp. 71-84, (2001) (PubMed).

    Iborra, Jackson, Cook: "The path of RNA through nuclear pores: apparent entry from the sides into specialized pores." in: Journal of cell science, Vol. 113 Pt 2, pp. 291-302, (2000) (PubMed).

  • Target
    NUP62 (Nucleoporin 62kDa (NUP62))
    Andere Bezeichnung
    Nucleoporin p62 (NUP62 Produkte)
    Synonyme
    IBSN antikoerper, SNDI antikoerper, p62 antikoerper, NUP62 antikoerper, AA589433 antikoerper, AI426861 antikoerper, AI790512 antikoerper, AU045898 antikoerper, D7Ertd649e antikoerper, Nupc1 antikoerper, CG6251 antikoerper, Dmel\\CG6251 antikoerper, DDBDRAFT_0167902 antikoerper, DDBDRAFT_0237712 antikoerper, DDB_0167902 antikoerper, DDB_0237712 antikoerper, nup62 antikoerper, Np62 antikoerper, nucleoporin 62 antikoerper, hypothetical protein antikoerper, nucleoporin 62kDa antikoerper, Nucleoporin 62kD antikoerper, predicted protein antikoerper, nuclear pore protein antikoerper, Nup62 nuclear pore complex glycoprotein p62-related protein (IC) antikoerper, Nuclear pore glycoprotein p62 antikoerper, NUP62 antikoerper, PGTG_03077 antikoerper, Nup62 antikoerper, nup62 antikoerper
    Hintergrund
    The nuclear pore complex (NPC) acts as a gate to mediate active transport of proteins and RNA into and out of the nucleus. Proteins actively transported into the nucleus through the NPC require specific nuclear localization sequences. Many of these nucleoporins contain N-acetylglucosamine (GlcNAc) residues that are O-linked to serine or threonine. p62 is the best characterized member of a group of nucleoporins that line the central region of the NPC. A tightly associated complex is formed by p62 and two other nucleoporins, p54 and p58. p54 binds to a carboxy-terminal coiled-coil domain of p62 and p58 binds to a dimer of p54. The amino-terminal domain of p62 contains a series of XFXFX repeats and is joined to the coiled-coil domain by a threonine-rich linker segment. The major role of p62 is maintenance of the structural integrity of NPCs.
    Molekulargewicht
    62 kDa
    Pathways
    EGFR Signaling Pathway, SARS-CoV-2 Protein Interaktom
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