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P-Cadherin Antikörper (AA 72-259)

CDH3 Reaktivität: Human, Ratte WB, IHC, IF, IP Wirt: Maus Monoclonal 56-P unconjugated
Produktnummer ABIN967840
  • Target Alle P-Cadherin (CDH3) Antikörper anzeigen
    P-Cadherin (CDH3)
    Bindungsspezifität
    • 16
    • 15
    • 11
    • 9
    • 9
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 72-259
    Reaktivität
    • 102
    • 45
    • 10
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    Human, Ratte
    Wirt
    • 93
    • 16
    • 2
    Maus
    Klonalität
    • 94
    • 17
    Monoklonal
    Konjugat
    • 48
    • 12
    • 11
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser P-Cadherin Antikörper ist unkonjugiert
    Applikation
    • 99
    • 52
    • 43
    • 41
    • 20
    • 18
    • 13
    • 13
    • 9
    • 9
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    Kreuzreaktivität
    Ratte (Rattus)
    Produktmerkmale
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    Aufreinigung
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogen
    Human P-Cadherin aa. 72-259
    Klon
    56-P
    Isotyp
    IgG1
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    Related Products: ABIN968533, ABIN967389

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    250 μg/mL
    Buffer
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store undiluted at -20°C.
  • Holsinger, Ward, Duffield, Zachwieja, Jallal: "The transmembrane receptor protein tyrosine phosphatase DEP1 interacts with p120(ctn)." in: Oncogene, Vol. 21, Issue 46, pp. 7067-76, (2002) (PubMed).

    Bailey, Biddlestone, Shepherd, Barr, Warner, Jankowski: "Altered cadherin and catenin complexes in the Barrett's esophagus-dysplasia-adenocarcinoma sequence: correlation with disease progression and dedifferentiation." in: The American journal of pathology, Vol. 152, Issue 1, pp. 135-44, (1998) (PubMed).

    Kantak, Kramer: "E-cadherin regulates anchorage-independent growth and survival in oral squamous cell carcinoma cells." in: The Journal of biological chemistry, Vol. 273, Issue 27, pp. 16953-61, (1998) (PubMed).

    Tao, Edwards, Tubb, Wang, Bryan, McCrea: "beta-Catenin associates with the actin-bundling protein fascin in a noncadherin complex." in: The Journal of cell biology, Vol. 134, Issue 5, pp. 1271-81, (1996) (PubMed).

    Nose, Nagafuchi, Takeichi: "Isolation of placental cadherin cDNA: identification of a novel gene family of cell-cell adhesion molecules." in: The EMBO journal, Vol. 6, Issue 12, pp. 3655-61, (1988) (PubMed).

  • Target
    P-Cadherin (CDH3)
    Andere Bezeichnung
    P-Cadherin (CDH3 Produkte)
    Synonyme
    CDH3 antikoerper, Cadherin-3 antikoerper, AI385538 antikoerper, Cadp antikoerper, Cdhp antikoerper, P-cadherin antikoerper, Pcad antikoerper, CDHP antikoerper, HJMD antikoerper, PCAD antikoerper, E-Cad antikoerper, E-cadherin antikoerper, EP-cadherin antikoerper, XTCAD-1 antikoerper, c-cadherin antikoerper, cadherin-1 antikoerper, cdh1 antikoerper, cdh1-b antikoerper, cdh3 antikoerper, cdhc-A antikoerper, cdhp antikoerper, hjmd antikoerper, l-cam antikoerper, lcam antikoerper, pcad antikoerper, uvo antikoerper, uvomorulin antikoerper, xb-cad antikoerper, xcdh1 antikoerper, CDH15 antikoerper, K-CAM antikoerper, cadherin 3 antikoerper, cadherin 3 L homeolog antikoerper, Cadherin-3 antikoerper, CDH3 antikoerper, Cdh3 antikoerper, cdh3.L antikoerper, cdh-3 antikoerper
    Hintergrund
    Cadherins are a family of transmembrane glycoproteins involved in the Ca2+-dependent cell-cell adhesion that occurs in many tissues. Cadherins are similar in their domain structure, Ca2+ and protease sensitivity, and molecular weight. However, these proteins have distinct tissue expression patterns and immunological reactivities. P-Cadherin is localized in placenta while E-Cadherin and N-Cadherin are found in epithelial and neural tissues, respectively. P-Cadherin is an 829 amino acid polypeptide with a putative signal peptide and precursor region, an extracellular domain containing several internal repeats, and a highly hydrophobic transmembrane region. The cytoplasmic domain provides a link to the cytoskeleton through the associated catenin proteins.
    Molekulargewicht
    120 kDa
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