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FOXA2 Antikörper

FOXA2 Reaktivität: Human, Maus WB, BI, ICS Wirt: Maus Monoclonal N17-280 unconjugated
Produktnummer ABIN967680
  • Target Alle FOXA2 Antikörper anzeigen
    FOXA2 (Forkhead Box A2 (FOXA2))
    Reaktivität
    • 91
    • 26
    • 15
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Human, Maus
    Wirt
    • 85
    • 7
    • 2
    Maus
    Klonalität
    • 78
    • 16
    Monoklonal
    Konjugat
    • 47
    • 7
    • 6
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FOXA2 Antikörper ist unkonjugiert
    Applikation
    • 85
    • 50
    • 40
    • 25
    • 15
    • 14
    • 13
    • 10
    • 7
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), BioImaging (BI), Intracellular Staining (ICS)
    Marke
    BD Pharmingen™
    Kreuzreaktivität (Details)
    Predicted: Mouse
    Produktmerkmale
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Sodium azide is a reversible inhibitor of oxidative metabolism, therefore, antibody preparations containing this preservative agent must not be used in cell cultures nor injected into animals. Sodium azide may be removed by washing stained cells or plate-bound antibody or dialyzing soluble antibody in sodium azide-free buffer. Since endotoxin may also affect the results of functional studies, we recommend the NA/LE (No Azide/Low Endotoxin) antibody format, if available, for in vitro and in vivo use.
    4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    5. Triton is a trademark of the Dow Chemical Company.
    Aufreinigung
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogen
    Human FoxA2 Peptide
    Klon
    N17-280
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product FOXA2 Primärantikörper
  • Kommentare

    Related Products: ABIN967389

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store undiluted at 4°C.
  • Burtscher, Lickert: "Foxa2 regulates polarity and epithelialization in the endoderm germ layer of the mouse embryo." in: Development (Cambridge, England), Vol. 136, Issue 6, pp. 1029-38, (2009) (PubMed).

    Lin, Metzakopian, Mavromatakis, Gao, Balaskas, Sasaki, Briscoe, Whitsett, Goulding, Kaestner, Ang: "Foxa1 and Foxa2 function both upstream of and cooperatively with Lmx1a and Lmx1b in a feedforward loop promoting mesodiencephalic dopaminergic neuron development." in: Developmental biology, Vol. 333, Issue 2, pp. 386-96, (2009) (PubMed).

    DAmour, Agulnick, Eliazer, Kelly, Kroon, Baetge: "Efficient differentiation of human embryonic stem cells to definitive endoderm." in: Nature biotechnology, Vol. 23, Issue 12, pp. 1534-41, (2005) (PubMed).

    Thomson, Itskovitz-Eldor, Shapiro, Waknitz, Swiergiel, Marshall, Jones: "Embryonic stem cell lines derived from human blastocysts." in: Science (New York, N.Y.), Vol. 282, Issue 5391, pp. 1145-7, (1998) (PubMed).

    Monaghan, Kaestner, Grau, Schütz: "Postimplantation expression patterns indicate a role for the mouse forkhead/HNF-3 alpha, beta and gamma genes in determination of the definitive endoderm, chordamesoderm and neuroectoderm." in: Development (Cambridge, England), Vol. 119, Issue 3, pp. 567-78, (1994) (PubMed).

    Clevidence, Overdier, Tao, Qian, Pani, Lai, Costa: "Identification of nine tissue-specific transcription factors of the hepatocyte nuclear factor 3/forkhead DNA-binding-domain family." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 9, pp. 3948-52, (1993) (PubMed).

    Lai, Prezioso, Tao, Chen, Darnell: "Hepatocyte nuclear factor 3 alpha belongs to a gene family in mammals that is homologous to the Drosophila homeotic gene fork head." in: Genes & development, Vol. 5, Issue 3, pp. 416-27, (1991) (PubMed).

  • Target
    FOXA2 (Forkhead Box A2 (FOXA2))
    Andere Bezeichnung
    FOXA2 (FOXA2 Produkte)
    Synonyme
    hnf3b antikoerper, tcf3b antikoerper, hnf3beta antikoerper, hnf3-beta antikoerper, FOXA2 antikoerper, HNF3B antikoerper, TCF3B antikoerper, HNF-3B antikoerper, ax antikoerper, axl antikoerper, fkd1 antikoerper, ik:tdsubc_2g8 antikoerper, tdsubc_2g8 antikoerper, wu:fe05g04 antikoerper, xx:tdsubc_2g8 antikoerper, FoxA2-A antikoerper, FoxA2a antikoerper, xFD-3 antikoerper, xbeta-1 antikoerper, HNF-3b antikoerper, HNF3-beta antikoerper, HNF3beta antikoerper, Hnf-3b antikoerper, Hnf3b antikoerper, Tcf-3b antikoerper, Tcf3b antikoerper, HNF-3BETA antikoerper, forkhead box A2 antikoerper, forkhead box A2 L homeolog antikoerper, foxa2 antikoerper, FOXA2 antikoerper, foxa2.L antikoerper, Foxa2 antikoerper
    Hintergrund
    FoxA2, forkhead box A2, is a member of the forkhead class of DNA-binding proteins that regulates gene expression in the liver, pancreatic islets, adipocytes and some neural cells. This hepatocyte nuclear factor is a transcriptional activator for liver-specific genes such as alpha fetoprotein, albumin, tyrosine aminotransferase and transthyretin. FoxA2 is expressed in embryonic endoderm, the germ layer that gives rise to the digestive system, and contributes to the specification of the pancreas and the regulation of glucose homoeostasis. FoxA2 also has roles in neural development. Specifically, FoxA2 cooperates with related FoxA1 in the specification and differentiation of midbrain dopaminergic neurons in a dosage-dependent manner.
    Synonyms: Forkhead box A2, HNF3B, HNF-3B, HNF-3beta, hepatocyte nuclear factor 3beta
    Molekulargewicht
    48 kDa
    Pathways
    Dopaminergic Neurogenesis, Regulation of Carbohydrate Metabolic Process
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