Integrin beta 3 Antikörper

Produktnummer ABIN967485

Produktdetails anti-Integrin beta 3 Antikörper

Target: Integrin beta 3 (ITGB3)

Reaktivität: Human, Rind (Kuh), Pavian, Cynomolgus, Rhesusaffen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Integrin beta 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Marke: BD Pharmingen™

Produktmerkmale: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Klon: VI-PL2

Isotyp: IgG1 kappa

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 4° C.

Referenzen für anti-Integrin beta 3 Antikörper (ABIN967485)

Mason, André, Bensussan, Buckley, Civin, Clark, de Haas, Goyert, Hadam, Hart, Horejsí, Meuer, Morissey, Schwartz-Albiez, Shaw, Simmons, Uguccioni, van der Schoot, Viver, Zola: "CD antigens 2001." in: Tissue antigens, Vol. 58, Issue 6, pp. 425-30, (2002) (PubMed).

Details zu Integrin beta 3

Target: Integrin beta 3 (ITGB3)

Andere Bezeichnung: CD61 (ITGB3 Produkte)

Synonyme: BDPLT16 antikoerper, BDPLT2 antikoerper, CD61 antikoerper, GP3A antikoerper, GPIIIa antikoerper, GT antikoerper, INGRB3 antikoerper, integrin antikoerper, INTB3 antikoerper, GPIIIA antikoerper, cd61 antikoerper, gp3a antikoerper, itgb3 antikoerper, itgb3.2 antikoerper, itgb3.1 antikoerper, integrin subunit beta 3 antikoerper, integrin beta 3 antikoerper, integrin subunit beta 3 L homeolog antikoerper, integrin beta 3a antikoerper, integrin beta 3b antikoerper, ITGB3 antikoerper, Itgb3 antikoerper, itgb3.L antikoerper, itgb3a antikoerper, itgb3b antikoerper

Hintergrund: Reacts with integrin beta3, a 105 kDa transmembrane glycoprotein, expressed on platelets, megakaryocytes, osteoclasts and endothelia. Integrin beta3 associates with gpIIa (CD41) to form the CD41/CD61 complex which mediates platelet adhesion and aggregation. CD61 also associates with CD51 to form the CD51/CD61 complex (vitronectin receptor). CD61 appears to bind to fibrinogen, fibronectin, vWF, vitronectin, and thrombospondin to mediate cell adhesion. This antibody is routinely tested by flow cytometric analysis.
Synonyms: Integrin beta3 Chain

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex