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LAMP1 Antikörper

LAMP1 Reaktivität: Maus WB, IP, IHC (fro), ICS, IAC Wirt: Ratte Monoclonal 1D4B unconjugated
Produktnummer ABIN967382
  • Target Alle LAMP1 Antikörper anzeigen
    LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))
    Reaktivität
    • 106
    • 65
    • 37
    • 27
    • 8
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 67
    • 56
    • 24
    • 1
    Ratte
    Klonalität
    • 100
    • 48
    Monoklonal
    Konjugat
    • 52
    • 15
    • 15
    • 12
    • 9
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser LAMP1 Antikörper ist unkonjugiert
    Applikation
    • 92
    • 75
    • 41
    • 33
    • 26
    • 25
    • 25
    • 15
    • 15
    • 13
    • 13
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Intracellular Staining (ICS), Immunoaffinity Chromatography (IAC)
    Marke
    BD Pharmingen™
    Produktmerkmale
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    Aufreinigung
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogen
    Plasma membrane fraction of mouse embryo NIH 3T3 cell line
    Klon
    1D4B
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product LAMP1 Primärantikörper
  • Applikationshinweise
    This antibody conjugate has been tested by intracellular immunofluorescent staining ( Less or equal than 1 µg/million cells, using the Cytofix/Cytoperm™ Kit) with flow cytometric analysis to assure specificity and reactivity.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store undiluted at 4° C.
  • Rohrer, Schweizer, Russell, Kornfeld: "The targeting of Lamp1 to lysosomes is dependent on the spacing of its cytoplasmic tail tyrosine sorting motif relative to the membrane." in: The Journal of cell biology, Vol. 132, Issue 4, pp. 565-76, (1996) (PubMed).

    Arterburn, Earles, August: "The disulfide structure of mouse lysosome-associated membrane protein 1." in: The Journal of biological chemistry, Vol. 265, Issue 13, pp. 7419-23, (1990) (PubMed).

    Chen, Chen, DSouza, Murphy, August: "Lysosomal membrane glycoproteins: properties of LAMP-1 and LAMP-2." in: Biochemical Society symposium, Vol. 51, pp. 97-112, (1987) (PubMed).

    Chen, Pan, DSouza, August: "Lysosome-associated membrane proteins: characterization of LAMP-1 of macrophage P388 and mouse embryo 3T3 cultured cells." in: Archives of biochemistry and biophysics, Vol. 239, Issue 2, pp. 574-86, (1985) (PubMed).

  • Target
    LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))
    Andere Bezeichnung
    CD107a (LAMP1 Produkte)
    Synonyme
    CD107a antikoerper, LAMPA antikoerper, LGP120 antikoerper, AI196048 antikoerper, Lamp-1 antikoerper, LEP100 antikoerper, LAMP-1 antikoerper, LGP-A antikoerper, Lgpa antikoerper, Lysosome-associated membrane protein 1 antikoerper, cd107a antikoerper, lamp-1 antikoerper, lamp1 antikoerper, lampa antikoerper, lgp120 antikoerper, rexp76 antikoerper, lysosomal associated membrane protein 1 antikoerper, lysosomal-associated membrane protein 1 antikoerper, lysosomal-associated membrane protein 1 L homeolog antikoerper, LAMP1 antikoerper, Lamp1 antikoerper, lamp1.L antikoerper
    Hintergrund
    The 1D4B antibody recognizes CD107a (Lysosome-Associated Membrane Protein 1, LAMP-1), one of the two major glycoproteins in lysosome membranes which are useful markers to distinguish lysosomes from other organelles. Mouse CD107a consists of a 40-kDa core protein which is heavily glycosylated to form heterogeneous mature glycoprotein of 110-140 kDa. It is principally expressed in epithelial cells and macrophages in a variety of organs in normal and Beige mutant mice. Several lines of evidence suggest that cell-surface mouse and human LAMP-1 glycoproteins, the expression of which may correlate with malignant transformation, participate in intercellular adhesion and adhesion to extracellular matrix.
    Synonyms: LAMP-1
    Pathways
    Autophagie
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