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ITGB1 Antikörper

ITGB1 Reaktivität: Maus WB, FACS, IP, IHC (p), Func Wirt: Ratte Monoclonal 9EG7 unconjugated
Produktnummer ABIN967378
  • Target Alle ITGB1 Antikörper anzeigen
    ITGB1 (Integrin beta 1 (ITGB1))
    Reaktivität
    • 221
    • 111
    • 88
    • 22
    • 20
    • 20
    • 18
    • 12
    • 10
    • 10
    • 10
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 159
    • 79
    • 20
    • 8
    • 7
    • 1
    Ratte
    Klonalität
    • 146
    • 123
    • 1
    Monoklonal
    Konjugat
    • 119
    • 25
    • 25
    • 16
    • 10
    • 9
    • 9
    • 8
    • 6
    • 6
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser ITGB1 Antikörper ist unkonjugiert
    Applikation
    • 135
    • 122
    • 77
    • 50
    • 39
    • 31
    • 29
    • 27
    • 26
    • 21
    • 16
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func)
    Marke
    BD Pharmingen™
    Produktmerkmale
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    Aufreinigung
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogen
    Mouse endothelial cell line
    Klon
    9EG7
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product ITGB1 Primärantikörper
  • Applikationshinweise
    For IHC, we recommend the use of purified 9EG7 mAb in our special formulation for immunohistochemistry.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store undiluted at 4° C.
  • Yashiro, Tai, Toyo-oka, Park, Abe, Hamaoka, Kobayashi, Neben, Fujiwara: "A fundamental difference in the capacity to induce proliferation of naive T cells between CD28 and other co-stimulatory molecules." in: European journal of immunology, Vol. 28, Issue 3, pp. 926-35, (1998) (PubMed).

    Driessens, Van Rijthoven, Kemperman, Roos: "Adhesion of lymphoma cells to fibronectin: differential use of alpha 4 beta 1 and alpha 5 beta 1 integrins and stimulation by the 9EG7 mAb against the murine beta 1 integrin subunit." in: Cell adhesion and communication, Vol. 3, Issue 4, pp. 327-36, (1996) (PubMed).

    Milner, Edwards, Streuli, Ffrench-Constant: "A role in migration for the alpha V beta 1 integrin expressed on oligodendrocyte precursors." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 16, Issue 22, pp. 7240-52, (1996) (PubMed).

    Rich, Van Nood, Lee: "Role of alpha 5 beta 1 integrin in TGF-beta 1-costimulated CD8+ T cell growth and apoptosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 157, Issue 7, pp. 2916-23, (1996) (PubMed).

    Kassner, Kawaguchi, Hemler: "Minimum alpha chain cytoplasmic tail sequence needed to support integrin-mediated adhesion." in: The Journal of biological chemistry, Vol. 269, Issue 31, pp. 19859-67, (1994) (PubMed).

    Lenter, Vestweber: "The integrin chains beta 1 and alpha 6 associate with the chaperone calnexin prior to integrin assembly." in: The Journal of biological chemistry, Vol. 269, Issue 16, pp. 12263-8, (1994) (PubMed).

    Springer: "Adhesion receptors of the immune system." in: Nature, Vol. 346, Issue 6283, pp. 425-34, (1990) (PubMed).

  • Target
    ITGB1 (Integrin beta 1 (ITGB1))
    Andere Bezeichnung
    CD29 (ITGB1 Produkte)
    Synonyme
    CD29 antikoerper, FNRB antikoerper, GPIIA antikoerper, MDF2 antikoerper, MSK12 antikoerper, VLA-BETA antikoerper, VLAB antikoerper, 4633401G24Rik antikoerper, AA409975 antikoerper, AA960159 antikoerper, ENSMUSG00000051907 antikoerper, Fnrb antikoerper, Gm9863 antikoerper, gpIIa antikoerper, cd29 antikoerper, fnrb antikoerper, gpiia antikoerper, itgb1 antikoerper, mdf2 antikoerper, msk12 antikoerper, vla-beta antikoerper, vlab antikoerper, itgb1-a antikoerper, itgb1-b antikoerper, integrin subunit beta 1 antikoerper, integrin beta 1 (fibronectin receptor beta) antikoerper, integrin subunit beta 1 S homeolog antikoerper, integrin beta 1 antikoerper, integrin subunit beta 1 L homeolog antikoerper, ITGB1 antikoerper, Itgb1 antikoerper, itgb1.S antikoerper, LOC100009173 antikoerper, itgb1.L antikoerper
    Hintergrund
    The 9EG7 antibody reacts with the 130-kDa integrin beta1 chain (CD29). CD29 is expressed on the cell surface as a heterodimer with one of the distinct integrin alpha chains. With alpha1 through alpha6 (CD49a through CD49f), it forms the VLA-1 through VLA-6 complexes, respectively, and with alphav (CD51), it forms alphavbeta1 integrin. It also associates with the integrin alpha7 alpha8 and alpha9 chains in non-lymphoid tissues. As a result, CD29 has a broad tissue distribution, including lymphocytes, endothelia, smooth muscle, and epithelia. 9EG7 mAb has been shown to inhibit both the alpha6beta1-mediated binding of lymphocytes to endothelial cells and the adhesion mediated by activated, but not unactivated, alpha4beta1-integrin. The source of the immunogen was mouse lymph node-derived endothelial cell line TME.
    Synonyms: Integrin beta1 chain
    Pathways
    Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interaktom
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