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IL1R1 Antikörper

IL1R1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal hIL1R-M1 unconjugated
Produktnummer ABIN967343
  • Target Alle IL1R1 Antikörper anzeigen
    IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
    Reaktivität
    • 119
    • 68
    • 53
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 113
    • 13
    • 10
    • 5
    • 2
    • 1
    Maus
    Klonalität
    • 120
    • 24
    Monoklonal
    Konjugat
    • 61
    • 17
    • 11
    • 8
    • 8
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Dieser IL1R1 Antikörper ist unkonjugiert
    Applikation
    • 123
    • 64
    • 47
    • 39
    • 16
    • 15
    • 13
    • 13
    • 11
    • 8
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Marke
    BD Pharmingen™
    Produktmerkmale
    1. Please refer to us for technical protocols.
    2. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    Aufreinigung
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Klon
    HIL1R-M1
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product IL1R1 Primärantikörper
  • Applikationshinweise
    ELISA Capture: The purified HIL1R-M1 antibody (ABIN967343) is useful as a capture antibody for a sandwich ELISA for measuring human IL-1 receptor I protein levels. Purified HIL1R-M1 antibody can be paired with a biotinylated detecting antibody, with recombinant soluble human IL-1 receptor type I as the standard. Purified HIL1R-M1 antibody should be titrated between 1 - 4 µg/ml to determine its optimal concentration for ELISA capture. To obtain linear standard curves, doubling dilutions of recombinant human IL-1 receptor type I ranging from 3000 to 20 pg/ml are recommended for inclusion in each ELISA plate.
    Note: This ELISA antibody pair shows no cross-reactivity with the following recombinant human cytokines: sCD14, CD40, CD40L, IL-1Ra, IL-1RII, IL-1alpha, IL-1beta, IL-2, IL-3, IL-4, sIL-4R, IL-5, IL-6, IL-6R, IL-7, IL-8, IL-10, IL-12p40, IL-12p70, IL-13, IL-15, TNF, LT-alpha, sTNFRI, sTNFRII, IFNgamma, TRAIL, GM-CSF, TGFbeta, Trx Western Blot: The purified HIL1R-M1.1 antibody (ABIN967343) has been reported to be useful for Western blotting, however, the antibody is not routinely tested for this application.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store undiluted at 4°C.
  • Sims: "CD121a." in: Journal of biological regulators and homeostatic agents, Vol. 14, Issue 2, pp. 133-5, (2000) (PubMed).

    Sims, Painter, Gow: "Genomic organization of the type I and type II IL-1 receptors." in: Cytokine, Vol. 7, Issue 6, pp. 483-90, (1996) (PubMed).

    Sims, Giri, Dower: "The two interleukin-1 receptors play different roles in IL-1 actions." in: Clinical immunology and immunopathology, Vol. 72, Issue 1, pp. 9-14, (1994) (PubMed).

  • Target
    IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
    Andere Bezeichnung
    CD121a (IL1R1 Produkte)
    Synonyme
    CD121A antikoerper, D2S1473 antikoerper, IL-1R-alpha antikoerper, IL1R antikoerper, IL1RA antikoerper, P80 antikoerper, CD121a antikoerper, CD121b antikoerper, IL-iR antikoerper, Il1r-1 antikoerper, DER4 antikoerper, Fit-1 antikoerper, Ly84 antikoerper, ST2L antikoerper, St2 antikoerper, St2-rs1 antikoerper, T1 antikoerper, T1/ST2 antikoerper, interleukin 1 receptor type 1 antikoerper, interleukin 1 receptor, type I antikoerper, interleukin 1 receptor-like 1 antikoerper, IL1R1 antikoerper, Il1r1 antikoerper, Il1rl1 antikoerper
    Hintergrund
    The HIL1R-M1 antibody reacts with recombinant and natural soluble CD121a which is also known as human IL-1 receptor type I proteins. Human IL-1 receptor type I serves as the ligand-binding chain of the IL-1 heterodimer complex. When produced by proteolytic cleavage, soluble forms of the IL-1R type I are found the circulation of healthy individuals and in excessive levels during inflammatory diseases. The human IL-1 receptor type I is also expressed predominantly by T lymphocytes, fibroblasts, and endothelial cells.
    Synonyms: IL-1 Receptor Type 1
    Pathways
    NF-kappaB Signalweg, Carbohydrate Homeostasis, Cancer Immune Checkpoints
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