NAMPT Antikörper

Produktnummer ABIN967254

Produktdetails anti-NAMPT Antikörper

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Reaktivität: Human

Wirt: Bitte anfragen

Klonalität: Monoklonal

Konjugat: Dieser NAMPT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: Ni-NTA purified truncated recombinant Visfatin expressed in E. Coli strain BL21 (DE3)

Aufreinigung: Antibodies are purified by protein A affinity chromatography

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Blot: Dilution 1: 2,00- 1: 1,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: -20 °C

Referenzen für anti-NAMPT Antikörper (ABIN967254)

Jin, Zhuo, Guo, Field: "p21-activated Kinase 1 (Pak1)-dependent phosphorylation of Raf-1 regulates its mitochondrial localization, phosphorylation of BAD, and Bcl-2 association." in: The Journal of biological chemistry, Vol. 280, Issue 26, pp. 24698-705, (2005) (PubMed).

Antignani, Youle: "A chimeric protein induces tumor cell apoptosis by delivering the human Bcl-2 family BH3-only protein Bad." in: Biochemistry, Vol. 44, Issue 10, pp. 4074-82, (2005) (PubMed).

Details zu NAMPT

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Andere Bezeichnung: Visfatin (NAMPT Produkte)

Synonyme: 1110035O14Rik antikoerper, PBEF antikoerper, PBEF1 antikoerper, VF antikoerper, VISFATIN antikoerper, AI314458 antikoerper, AI480535 antikoerper, NAmPRTase antikoerper, Pbef antikoerper, Pbef1 antikoerper, Visfatin antikoerper, visfatin antikoerper, pbef antikoerper, pbef1 antikoerper, nicotinamide phosphoribosyltransferase antikoerper, Nicotinamide phosphoribosyltransferase antikoerper, nicotinamide phosphoribosyltransferase S homeolog antikoerper, NAMPT antikoerper, Nampt antikoerper, nampt antikoerper, Smon_0680 antikoerper, Mrub_2845 antikoerper, Cseg_3704 antikoerper, BC1002_3997 antikoerper, Ftrac_2686 antikoerper, Varpa_5681 antikoerper, Celal_3900 antikoerper, Deima_0880 antikoerper, BC1001_3724 antikoerper, Celly_1696 antikoerper, Clole_1542 antikoerper, Tsp_05934 antikoerper, nampt.S antikoerper

Hintergrund: Visfatin, a newly identified adipocytokine ,which is predominantly secreted from visceral adipose tissue both in humans and mice . Visfatin corresponds to a protein identified previously as pre-B cell colony-enhancing factor (PBEF). Visfatin exerted insulin-mimetic effects in cultured cells, various insulin-sensitive tissues such as liver, muscle, and fat ,and lowered plasma glucose levels in mice. Mice heterozygous for a targeted mutation in the visfatin gene had modestly higher levels of plasma glucose relative to wild-type littermates. visfatin binds to and activates the insulin receptor. Which may lead to new insights into glucose homeostasis and/or new therapies for metabolic disorders such as diabetes.

Gen-ID: 10135