STAT1
Reaktivität: Human
WB, ELISA, IF
Wirt: Maus
Monoclonal
1A8
unconjugated
Applikationshinweise
WB: 1:500~1:1000 IHC: 1:50~1:100.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
100ug/100ul.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Yuan, Shioya, Ishiko, Sun, Gu, Huang, Lu, Kharbanda, Weichselbaum, Kufe: "p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage." in: Nature, Vol. 399, Issue 6738, pp. 814-7, (1999) (PubMed).
Quelle, Thierfelder, Witthuhn, Tang, Cohen, Ihle: "Phosphorylation and activation of the DNA binding activity of purified Stat1 by the Janus protein-tyrosine kinases and the epidermal growth factor receptor." in: The Journal of biological chemistry, Vol. 270, Issue 35, pp. 20775-80, (1995) (PubMed).
Schindler, Fu, Improta, Aebersold, Darnell: "Proteins of transcription factor ISGF-3: one gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon alpha." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 16, pp. 7836-9, (1992) (PubMed).
Target
STAT1
(Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))