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SRA1 Antikörper

SRA1 Reaktivität: Human WB, ELISA, IHC Monoclonal unconjugated
Produktnummer ABIN967077
  • Target Alle SRA1 Antikörper anzeigen
    SRA1 (Steroid Receptor RNA Activator 1 (SRA1))
    Reaktivität
    • 28
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    Bitte anfragen
    Klonalität
    • 24
    • 4
    Monoklonal
    Konjugat
    • 18
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser SRA1 Antikörper ist unkonjugiert
    Applikation
    • 27
    • 19
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Spezifität
    Ni-NTA purified truncated recombinant SRA expressed in E. Coli strain BL21 (DE3
    Aufreinigung
    Crude ascites.
    Isotyp
    IgG1
    Top Product
    Discover our top product SRA1 Primärantikörper
  • Applikationshinweise
    Western Blot: 1: 500- 1: 2,000
    IHC(P): 1: 500- 1: 2,000
    IHC(F): 1: 500- 1: 2,000
    ELISA: Propose dilution 1: 10,000 Determining optimal working dilutions by titration test.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Lagerung
    -20 °C
  • Chooniedass-Kothari, Hamedani, Troup, Hubé, Leygue: "The steroid receptor RNA activator protein is expressed in breast tumor tissues." in: International journal of cancer. Journal international du cancer, Vol. 118, Issue 4, pp. 1054-9, (2006) (PubMed).

    Chooniedass-Kothari, Emberley, Hamedani, Troup, Wang, Czosnek, Hube, Mutawe, Watson, Leygue: "The steroid receptor RNA activator is the first functional RNA encoding a protein." in: FEBS letters, Vol. 566, Issue 1-3, pp. 43-7, (2004) (PubMed).

    Lanz, Chua, Barron, Söder, DeMayo, OMalley: "Steroid receptor RNA activator stimulates proliferation as well as apoptosis in vivo." in: Molecular and cellular biology, Vol. 23, Issue 20, pp. 7163-76, (2003) (PubMed).

  • Target
    SRA1 (Steroid Receptor RNA Activator 1 (SRA1))
    Andere Bezeichnung
    SRA (SRA1 Produkte)
    Synonyme
    SRA antikoerper, SRAP antikoerper, STRAA1 antikoerper, pp7684 antikoerper, AA959952 antikoerper, Sra antikoerper, Srap antikoerper, Straa1 antikoerper, Strra1 antikoerper, zgc:86613 antikoerper, steroid receptor RNA activator 1 antikoerper, steroid receptor RNA activator 1 S homeolog antikoerper, cytoplasmic FMR1 interacting protein 1 antikoerper, SRA1 antikoerper, Sra1 antikoerper, sra1 antikoerper, sra1.S antikoerper, CYFIP1 antikoerper
    Hintergrund
    Steroid receptor RNA activator 1 (SRA), with 237-amino acid protein (about 27kDa), belongs to the growing family of functional non-coding RNAs. SRA was originally described as the first functional noncoding RNA able to specifically coactivate the activity of steroid receptors. Specifically, SRA exists as both an RNA transcript that forms a complex with steroid receptor coactivator-1 and as a stably expressed protein. Its expression is strongly up-regulated in many human tumors of the breast, uterus, and ovary, suggesting a potential role in pathogenesis. Although coactivation of steroid-dependent transcription by SRA is accompanied by a proliferative response, overexpression is not in itself sufficient to induce turmorigenesis.
    Gen-ID
    10011
    Pathways
    EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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