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Retinoblastoma 1 Antikörper

RB1 Reaktivität: Human IHC, ELISA Wirt: Maus Monoclonal 7E4B8 unconjugated
Produktnummer ABIN966949
  • Target Alle Retinoblastoma 1 (RB1) Antikörper anzeigen
    Retinoblastoma 1 (RB1)
    Reaktivität
    • 301
    • 120
    • 101
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 252
    • 52
    Maus
    Klonalität
    • 238
    • 66
    Monoklonal
    Konjugat
    • 153
    • 19
    • 17
    • 16
    • 11
    • 11
    • 8
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Retinoblastoma 1 Antikörper ist unkonjugiert
    Applikation
    • 227
    • 132
    • 114
    • 80
    • 79
    • 42
    • 42
    • 36
    • 28
    • 20
    • 19
    • 9
    • 8
    • 6
    • 6
    • 6
    • 4
    • 2
    • 1
    Immunohistochemistry (IHC), ELISA
    Aufreinigung
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human RB expressed in E. Coli.
    Klon
    7E4B8
    Isotyp
    IgG1
    Top Product
    Discover our top product RB1 Primärantikörper
  • Applikationshinweise
    Immunohistochemistry: 1/200 - 1/1000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
  • Target
    Retinoblastoma 1 (RB1)
    Andere Bezeichnung
    RB (RB1 Produkte)
    Synonyme
    OSRC antikoerper, RB antikoerper, p105-Rb antikoerper, pRb antikoerper, pp110 antikoerper, Rb antikoerper, Rb-1 antikoerper, P105-RB antikoerper, PP110 antikoerper, RB11 antikoerper, zgc:154147 antikoerper, RB transcriptional corepressor 1 antikoerper, RB transcriptional corepressor like 1 antikoerper, retinoblastoma 1 antikoerper, RB1 antikoerper, RBL1 antikoerper, Rb1 antikoerper, rb1 antikoerper
    Hintergrund
    The Rb protein regulates differentiation, apoptosis, and cell cycle control by coordinating the cell cycle at G1-S with transcriptional machinery. During G1, cyclin D-dependent kinase-mediated phosphorylation of Rb at Ser-795 marks the conversion of Rb from a transcriptionally repressive, hypophosphorylated state to an inactive, phosphorylated state, which may be sustained through mitosis by differential phosphorylation of up to 16 putative serine or threonine residues. Pediatric cancer retinoblastoma and the formation of other human tumors can be attributed to mutations in the retinoblastoma tumor suppressor gene(Rb).
    Synonyms: RB, pRb, OSRC, pp110, p105-Rb, RB1
    Gen-ID
    5925
    Pathways
    Zellzyklus, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagie
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