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RAD51 Antikörper (Isoform 2)

RAD51 Reaktivität: Human, Maus IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN966939
  • Target Alle RAD51 Antikörper anzeigen
    RAD51 (DNA Repair Protein Homolog 1 (RAD51))
    Bindungsspezifität
    • 18
    • 15
    • 10
    • 8
    • 7
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Isoform 2
    Reaktivität
    • 123
    • 85
    • 44
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 105
    • 21
    • 1
    Kaninchen
    Klonalität
    • 98
    • 29
    Polyklonal
    Konjugat
    • 71
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser RAD51 Antikörper ist unkonjugiert
    Applikation
    • 94
    • 39
    • 29
    • 29
    • 24
    • 22
    • 20
    • 16
    • 10
    • 9
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Immunogen
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human RAD51 homolog protein isoform 2
    Top Product
    Discover our top product RAD51 Primärantikörper
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Lagerung
    4 °C
  • Liang, Caporaso, McMaster, Ng, Landgren, Yeager, Chanock, Goldin: "Common genetic variants in candidate genes and risk of familial lymphoid malignancies." in: British journal of haematology, Vol. 146, Issue 4, pp. 418-23, (2009) (PubMed).

    Rebbeck, Mitra, Domchek, Wan, Chuai, Friebel, Panossian, Spurdle, Chenevix-Trench, , Singer, Pfeiler, Neuhausen, Lynch, Garber, Weitzel, Isaacs, Couch, Narod, Rubinstein, Tomlinson, Ganz, Olopade, Tung, Blum, Greenberg, Nathanson, Daly: "Modification of ovarian cancer risk by BRCA1/2-interacting genes in a multicenter cohort of BRCA1/2 mutation carriers." in: Cancer research, Vol. 69, Issue 14, pp. 5801-10, (2009) (PubMed).

    Kovalenko, Plug, Haaf, Gonda, Ashley, Ward, Radding, Golub: "Mammalian ubiquitin-conjugating enzyme Ubc9 interacts with Rad51 recombination protein and localizes in synaptonemal complexes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 7, pp. 2958-63, (1996) (PubMed).

    Benson, Stasiak, West: "Purification and characterization of the human Rad51 protein, an analogue of E. coli RecA." in: The EMBO journal, Vol. 13, Issue 23, pp. 5764-71, (1995) (PubMed).

  • Target
    RAD51 (DNA Repair Protein Homolog 1 (RAD51))
    Andere Bezeichnung
    RAD51 homolog protein (RAD51 Produkte)
    Synonyme
    BRCC5 antikoerper, HRAD51 antikoerper, HsRad51 antikoerper, HsT16930 antikoerper, MRMV2 antikoerper, RAD51A antikoerper, RECA antikoerper, CRAD51 antikoerper, wu:fb38e12 antikoerper, zgc:77754 antikoerper, RGD1563603 antikoerper, ATRAD51 antikoerper, F22D1.20 antikoerper, F22D1_20 antikoerper, RAS associated with diabetes protein 51 antikoerper, AV304093 antikoerper, Rad51a antikoerper, Reca antikoerper, brcc5 antikoerper, rad51 antikoerper, rad51a antikoerper, reca antikoerper, xrad51 antikoerper, RAD51 recombinase antikoerper, RAS associated with diabetes protein 51 antikoerper, RAD51 recombinase L homeolog antikoerper, RAD51 antikoerper, rad51 antikoerper, Rad51 antikoerper, rad51.L antikoerper
    Hintergrund
    RAD51 homolog protein isoform 2 is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. RAD51 homolog protein isoform 2 is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Product
    Pathways
    DNA Reparatur
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