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MEK1 Antikörper (C-Term)

MAP2K1 Reaktivität: Human, Ratte WB, IHC (p), ICC Polyclonal unconjugated
Produktnummer ABIN966512
  • Target Alle MEK1 (MAP2K1) Antikörper anzeigen
    MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
    Bindungsspezifität
    • 46
    • 28
    • 28
    • 23
    • 22
    • 22
    • 20
    • 19
    • 18
    • 16
    • 15
    • 14
    • 12
    • 11
    • 10
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 353-367, C-Term
    Reaktivität
    • 376
    • 206
    • 200
    • 37
    • 30
    • 18
    • 16
    • 12
    • 12
    • 10
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Ratte
    Wirt
    Bitte anfragen
    Klonalität
    • 293
    • 87
    Polyklonal
    Konjugat
    • 181
    • 25
    • 22
    • 17
    • 15
    • 14
    • 14
    • 12
    • 12
    • 12
    • 12
    • 10
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MEK1 Antikörper ist unkonjugiert
    Applikation
    • 247
    • 124
    • 103
    • 68
    • 66
    • 47
    • 33
    • 32
    • 25
    • 15
    • 11
    • 10
    • 9
    • 7
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminal of human MAP2K1 (353-367aa), identical to the related mouse and rat sequence.
    Top Product
    Discover our top product MAP2K1 Primärantikörper
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Rekonstitution
    0.2ml of distilled water will yield a concentration of 500µg/ml.
    Buffer
    Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4
    Konservierungsmittel
    Thimerosal (Merthiolate), Sodium azide
    Lagerung
    -20 °C
  • Rampoldi, Zimbello, Bortoluzzi, Tiso, Valle, Lanfranchi, Danieli: "Chromosomal localization of four MAPK signaling cascade genes: MEK1, MEK3, MEK4 and MEKK5." in: Cytogenetics and cell genetics, Vol. 78, Issue 3-4, pp. 301-3, (1998) (PubMed).

    Zheng, Guan: "Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2." in: The Journal of biological chemistry, Vol. 268, Issue 15, pp. 11435-9, (1993) (PubMed).

  • Target
    MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
    Andere Bezeichnung
    MAP2K1 (MAP2K1 Produkte)
    Synonyme
    Mek1 antikoerper, CFC3 antikoerper, MAPKK1 antikoerper, MEK1 antikoerper, MKK1 antikoerper, PRKMK1 antikoerper, MEKK1 antikoerper, Prkmk1 antikoerper, mek-2 antikoerper, si:ch211-242m18.2 antikoerper, wu:fj56a12 antikoerper, wu:fj61b01 antikoerper, zgc:56557 antikoerper, ATMEK1 antikoerper, F20B18.180 antikoerper, F20B18_180 antikoerper, MAP kinase/ ERK kinase 1 antikoerper, MITOGEN ACTIVATED PROTEIN KINASE KINASE antikoerper, MITOGEN ACTIVATED PROTEIN KINASE KINASE 1 antikoerper, NMAPKK antikoerper, MEK antikoerper, mitogen activated protein kinase kinase 1 antikoerper, mitogen-activated protein kinase kinase 1 antikoerper, mitogen-activated protein kinase kinase 1 L homeolog antikoerper, MAP kinase/ ERK kinase 1 antikoerper, Map2k1 antikoerper, MAP2K1 antikoerper, map2k1.L antikoerper, map2k1 antikoerper, MEK1 antikoerper
    Hintergrund
    Dual specificity mitogen-activated protein kinase kinase 1 is an enzyme that in humans is encoded by the MAP2K1 gene. The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon activation by a wide variety of extra- and intracellular signals. As an essential component of the MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. Rampoldi et al. (1997) localized the MAP2K1 gene to 15q22.1-q22.33.
    Pathways
    MAPK Signalweg, RTK Signalweg, Interferon-gamma Pathway, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagie, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
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