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LKB1 Antikörper (C-Term)

STK11 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN966488
  • Target Alle LKB1 (STK11) Antikörper anzeigen
    LKB1 (STK11) (serine/threonine Kinase 11 (STK11))
    Bindungsspezifität
    • 27
    • 23
    • 20
    • 19
    • 16
    • 15
    • 15
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 183
    • 115
    • 63
    • 16
    • 15
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 188
    • 9
    Kaninchen
    Klonalität
    • 191
    • 6
    Polyklonal
    Konjugat
    • 81
    • 13
    • 11
    • 11
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    Dieser LKB1 Antikörper ist unkonjugiert
    Applikation
    • 151
    • 84
    • 65
    • 65
    • 38
    • 28
    • 21
    • 15
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Maus, Ratte (Rattus)
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase STK11 (STK11) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
    Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminal of human STK11, different from the mouse sequence by one amino acid.< br/>Immunogen was affinity purified.
    Isotyp
    IgG
    Top Product
    Discover our top product STK11 Primärantikörper
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide, Thimerosal (Merthiolate)
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.
  • Jenne, Reimann, Nezu, Friedel, Loff, Jeschke, Müller, Back, Zimmer: "Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase." in: Nature genetics, Vol. 18, Issue 1, pp. 38-43, (1998) (PubMed).

  • Target
    LKB1 (STK11) (serine/threonine Kinase 11 (STK11))
    Andere Bezeichnung
    Serine/threonine-protein kinase STK11 (STK11 Produkte)
    Synonyme
    pjs antikoerper, LKB1 antikoerper, XEEK1 antikoerper, Stk11 antikoerper, PJS antikoerper, hLKB1 antikoerper, AA408040 antikoerper, Lkb1 antikoerper, Par-4 antikoerper, R75140 antikoerper, mLKB1 antikoerper, wu:fj61a05 antikoerper, zgc:110180 antikoerper, xeek1 antikoerper, serine/threonine kinase 11 antikoerper, polarization-related protein LKB1 antikoerper, serine/threonine kinase 11 L homeolog antikoerper, STK11 antikoerper, stk11 antikoerper, LOC662493 antikoerper, Stk11 antikoerper, stk11.L antikoerper
    Hintergrund
    Serine/threonine kinase 11 or LKB1 is a protein kinase which in humans is encoded by the STK11 gene. The STK11/LKB1 gene, which encodes a member of the serine/threonine kinase, regulates cell polarity and functions as a tumour suppressor Smith et al. (1999) found that the mouse Lkb1 gene encodes a protein showing strong sequence similarity to human LKB1. Karuman et al. (2001) demonstrated that LKB1 physically associates with p53 (191170) and regulates specific p53-dependent apoptosis pathways. Jenne et al. (1998) determined that the STK11 gene extends over 23 kb of genomic DNA and is composed of 9 exons, which are transcribed in telomere-to-centromere direction. Smith et al. (1999) found that the mouse Lkb1 gene consists of 10 exons covering approximately 15 kb.
    Pathways
    AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effekt
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