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ITK Antikörper (AA 2-110)

ITK Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 5G12C4 unconjugated
Produktnummer ABIN966422
  • Target Alle ITK Antikörper anzeigen
    ITK (IL2-Inducible T-Cell Kinase (ITK))
    Bindungsspezifität
    • 14
    • 10
    • 9
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-110
    Reaktivität
    • 52
    • 20
    • 12
    • 6
    • 3
    Human
    Wirt
    • 63
    • 6
    • 2
    Maus
    Klonalität
    • 64
    • 7
    Monoklonal
    Konjugat
    • 32
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ITK Antikörper ist unkonjugiert
    Applikation
    • 44
    • 37
    • 14
    • 14
    • 12
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB), ELISA
    Aufreinigung
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of ITK (aa2-110) expressed in E. Coli.
    Klon
    5G12C4
    Isotyp
    IgG1
    Top Product
    Discover our top product ITK Primärantikörper
  • Applikationshinweise
    Western Bloting: 1/500 - 1/2000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
  • Graves, Siroux, Guerra, Klimecki, Martinez: "Association of atopy and eczema with polymorphisms in T-cell immunoglobulin domain and mucin domain-IL-2-inducible T-cell kinase gene cluster in chromosome 5 q 33." in: The Journal of allergy and clinical immunology, Vol. 116, Issue 3, pp. 650-6, (2005) (PubMed).

    Perez-Villar, ODay, Hewgill, Nadler, Kanner: "Nuclear localization of the tyrosine kinase Itk and interaction of its SH3 domain with karyopherin alpha (Rch1alpha)." in: International immunology, Vol. 13, Issue 10, pp. 1265-74, (2001) (PubMed).

  • Target
    ITK (IL2-Inducible T-Cell Kinase (ITK))
    Andere Bezeichnung
    ITK (ITK Produkte)
    Synonyme
    Emt antikoerper, Tcsk antikoerper, Tsk antikoerper, EMT antikoerper, LPFS1 antikoerper, LYK antikoerper, PSCTK2 antikoerper, IL2 inducible T cell kinase antikoerper, IL2 inducible T-cell kinase antikoerper, IL2-inducible T-cell kinase antikoerper, Itk antikoerper, ITK antikoerper
    Hintergrund
    ITK: IL2-inducible T-cell kinase. This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation.
    Synonyms: EMT, LYK, PSCTK2
    Gen-ID
    3702
    Pathways
    T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung
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