ITK
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
RB50773
unconjugated
Applikationshinweise
Western Bloting: 1/500 - 1/2000. ELISA: Propose dilution 1/10000. Not yet tested in other applications. Determining optimal working dilutions by titration test.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Graves, Siroux, Guerra, Klimecki, Martinez: "Association of atopy and eczema with polymorphisms in T-cell immunoglobulin domain and mucin domain-IL-2-inducible T-cell kinase gene cluster in chromosome 5 q 33." in: The Journal of allergy and clinical immunology, Vol. 116, Issue 3, pp. 650-6, (2005) (PubMed).
Perez-Villar, ODay, Hewgill, Nadler, Kanner: "Nuclear localization of the tyrosine kinase Itk and interaction of its SH3 domain with karyopherin alpha (Rch1alpha)." in: International immunology, Vol. 13, Issue 10, pp. 1265-74, (2001) (PubMed).
ITK: IL2-inducible T-cell kinase. This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. Synonyms: EMT, LYK, PSCTK2